| http://purl.uniprot.org/citations/11573960 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11573960 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11573960 | http://www.w3.org/2000/01/rdf-schema#comment | "IL-13 mediates its effects through a complex receptor system including IL-4Ralpha and a functional IL-13Ralpha1. IL-13 has been reported to have no effects on mouse B cells due to a lack of receptor expression. However, on human B cells a functional IL-13Ralpha1 has been described. Here, we identified the rat IL-13Ralpha1 in order to analyze its expression and function in rat B cells. The expression of IL-13Ralpha1 has been shown by the presence of mRNA and the corresponding protein in purified rat B cells and in rat hybridoma B cell line. Rat B cells are able to bind IL-13 and to proliferate when cultured with CD40 ligand and IL-13. In vivo experiments showed that administration of IL-13 did enhance IgE production. These results suggest a direct interaction of rat B cells with IL-13 through a functional receptor with an increase of IgE production and provide a relevant model to further study the activity of IL-13 and to better understand its role in human diseases."xsd:string |
| http://purl.uniprot.org/citations/11573960 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.2001.5682"xsd:string |
| http://purl.uniprot.org/citations/11573960 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.2001.5682"xsd:string |
| http://purl.uniprot.org/citations/11573960 | http://purl.uniprot.org/core/author | "Khalife J."xsd:string |
| http://purl.uniprot.org/citations/11573960 | http://purl.uniprot.org/core/author | "Khalife J."xsd:string |
| http://purl.uniprot.org/citations/11573960 | http://purl.uniprot.org/core/author | "Pierrot C."xsd:string |
| http://purl.uniprot.org/citations/11573960 | http://purl.uniprot.org/core/author | "Pierrot C."xsd:string |
| http://purl.uniprot.org/citations/11573960 | http://purl.uniprot.org/core/author | "Begue A."xsd:string |
| http://purl.uniprot.org/citations/11573960 | http://purl.uniprot.org/core/author | "Begue A."xsd:string |
| http://purl.uniprot.org/citations/11573960 | http://purl.uniprot.org/core/author | "Beniguel L."xsd:string |
| http://purl.uniprot.org/citations/11573960 | http://purl.uniprot.org/core/author | "Beniguel L."xsd:string |
| http://purl.uniprot.org/citations/11573960 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11573960 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11573960 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/11573960 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/11573960 | http://purl.uniprot.org/core/pages | "969-976"xsd:string |
| http://purl.uniprot.org/citations/11573960 | http://purl.uniprot.org/core/pages | "969-976"xsd:string |
| http://purl.uniprot.org/citations/11573960 | http://purl.uniprot.org/core/title | "Expression of a functional IL-13Ralpha1 by rat B cells."xsd:string |
| http://purl.uniprot.org/citations/11573960 | http://purl.uniprot.org/core/title | "Expression of a functional IL-13Ralpha1 by rat B cells."xsd:string |
| http://purl.uniprot.org/citations/11573960 | http://purl.uniprot.org/core/volume | "287"xsd:string |
| http://purl.uniprot.org/citations/11573960 | http://purl.uniprot.org/core/volume | "287"xsd:string |
| http://purl.uniprot.org/citations/11573960 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11573960 |
| http://purl.uniprot.org/citations/11573960 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11573960 |