| http://purl.uniprot.org/citations/11580899 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11580899 | http://www.w3.org/2000/01/rdf-schema#comment | "We previously reported that the cell surface proteoglycan syndecan-2 can induce dendritic spine formation in hippocampal neurons. We demonstrate here that the EphB2 receptor tyrosine kinase phosphorylates syndecan-2 and that this phosphorylation event is crucial for syndecan-2 clustering and spine formation. Syndecan-2 is tyrosine phosphorylated and forms a complex with EphB2 in mouse brain. Dominant-negative inhibition of endogenous EphB receptor activities blocks clustering of endogenous syndecan-2 and normal spine formation in cultured hippocampal neurons. This is the first evidence that Eph receptors play a physiological role in dendritic spine morphogenesis. Our observations suggest that spine morphogenesis is triggered by the activation of Eph receptors, which causes tyrosine phosphorylation of target molecules, such as syndecan-2, in presumptive spines."xsd:string |
| http://purl.uniprot.org/citations/11580899 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0896-6273(01)00440-8"xsd:string |
| http://purl.uniprot.org/citations/11580899 | http://purl.uniprot.org/core/author | "Yamaguchi Y."xsd:string |
| http://purl.uniprot.org/citations/11580899 | http://purl.uniprot.org/core/author | "Pasquale E.B."xsd:string |
| http://purl.uniprot.org/citations/11580899 | http://purl.uniprot.org/core/author | "Irie F."xsd:string |
| http://purl.uniprot.org/citations/11580899 | http://purl.uniprot.org/core/author | "Couchman J.R."xsd:string |
| http://purl.uniprot.org/citations/11580899 | http://purl.uniprot.org/core/author | "Ethell I.M."xsd:string |
| http://purl.uniprot.org/citations/11580899 | http://purl.uniprot.org/core/author | "Kalo M.S."xsd:string |
| http://purl.uniprot.org/citations/11580899 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11580899 | http://purl.uniprot.org/core/name | "Neuron"xsd:string |
| http://purl.uniprot.org/citations/11580899 | http://purl.uniprot.org/core/pages | "1001-1013"xsd:string |
| http://purl.uniprot.org/citations/11580899 | http://purl.uniprot.org/core/title | "EphB/syndecan-2 signaling in dendritic spine morphogenesis."xsd:string |
| http://purl.uniprot.org/citations/11580899 | http://purl.uniprot.org/core/volume | "31"xsd:string |
| http://purl.uniprot.org/citations/11580899 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11580899 |
| http://purl.uniprot.org/citations/11580899 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11580899 |
| http://purl.uniprot.org/uniprot/P34900#attribution-794FB0AB7075D6801553E369A2FD81AA | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/11580899 |
| http://purl.uniprot.org/uniprot/#_P52799-mappedCitation-11580899 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11580899 |
| http://purl.uniprot.org/uniprot/#_A0A8I6ASG6-mappedCitation-11580899 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11580899 |
| http://purl.uniprot.org/uniprot/#_A0A8I6B5M9-mappedCitation-11580899 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11580899 |
| http://purl.uniprot.org/uniprot/#_O15197-mappedCitation-11580899 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11580899 |
| http://purl.uniprot.org/uniprot/#_P34741-mappedCitation-11580899 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11580899 |
| http://purl.uniprot.org/uniprot/#_P34900-mappedCitation-11580899 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11580899 |
| http://purl.uniprot.org/uniprot/#_Q15768-mappedCitation-11580899 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11580899 |
| http://purl.uniprot.org/uniprot/#_P98172-mappedCitation-11580899 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11580899 |