| http://purl.uniprot.org/citations/11583593 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11583593 | http://www.w3.org/2000/01/rdf-schema#comment | "Human GLUT11 (encoded by the solute carrier 2A11 gene, SLC2A11) is a novel sugar transporter which exhibits significant sequence similarity with the members of the GLUT family. The amino acid sequence deduced from its cDNAs predicts 12 putative membrane-spanning helices and all the motifs (sugar-transporter signatures) that have previously been shown to be essential for sugar-transport activity. The closest relative of GLUT11 is the fructose transporter GLUT5 (sharing 41.7% amino acid identity with GLUT11). The human GLUT11 gene (SLC2A11) consists of 12 exons and is located on chromosome 22q11.2. In human tissues, a 7.2 kb transcript of GLUT11 was detected exclusively in heart and skeletal muscle. Transfection of COS-7 cells with GLUT11 cDNA significantly increased the glucose-transport activity reconstituted from membrane extracts as well as the specific binding of the sugar-transporter ligand cytochalasin B. In contrast to that of GLUT4, the glucose-transport activity of GLUT11 was markedly inhibited by fructose. It is concluded that GLUT11 is a novel, muscle-specific transport facilitator that is a member of the extended GLUT family of sugar/polyol-transport facilitators."xsd:string |
| http://purl.uniprot.org/citations/11583593 | http://purl.org/dc/terms/identifier | "doi:10.1042/0264-6021:3590443"xsd:string |
| http://purl.uniprot.org/citations/11583593 | http://purl.uniprot.org/core/author | "Joost H.G."xsd:string |
| http://purl.uniprot.org/citations/11583593 | http://purl.uniprot.org/core/author | "Schurmann A."xsd:string |
| http://purl.uniprot.org/citations/11583593 | http://purl.uniprot.org/core/author | "Eckel J."xsd:string |
| http://purl.uniprot.org/citations/11583593 | http://purl.uniprot.org/core/author | "Axer H."xsd:string |
| http://purl.uniprot.org/citations/11583593 | http://purl.uniprot.org/core/author | "Bocianski A."xsd:string |
| http://purl.uniprot.org/citations/11583593 | http://purl.uniprot.org/core/author | "Doege H."xsd:string |
| http://purl.uniprot.org/citations/11583593 | http://purl.uniprot.org/core/author | "Scheepers A."xsd:string |
| http://purl.uniprot.org/citations/11583593 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11583593 | http://purl.uniprot.org/core/name | "Biochem J"xsd:string |
| http://purl.uniprot.org/citations/11583593 | http://purl.uniprot.org/core/pages | "443-449"xsd:string |
| http://purl.uniprot.org/citations/11583593 | http://purl.uniprot.org/core/title | "Characterization of human glucose transporter (GLUT) 11 (encoded by SLC2A11), a novel sugar-transport facilitator specifically expressed in heart and skeletal muscle."xsd:string |
| http://purl.uniprot.org/citations/11583593 | http://purl.uniprot.org/core/volume | "359"xsd:string |
| http://purl.uniprot.org/citations/11583593 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11583593 |
| http://purl.uniprot.org/citations/11583593 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11583593 |
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