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http://purl.uniprot.org/citations/11584268http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11584268http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11584268http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Citation
http://purl.uniprot.org/citations/11584268http://www.w3.org/2000/01/rdf-schema#comment"Ero1 and Pdi1 are essential elements of the pathway for the formation of disulphide bonds within the endoplasmic reticulum (ER). By screening for alternative oxidation pathways in Saccharomyces cerevisiae, we identified ERV2 as a gene that when overexpressed can restore viability and disulphide bond formation to an ero1-1 mutant strain. ERV2 encodes a luminal ER protein of relative molecular mass 22,000. Purified recombinant Erv2p is a flavoenzyme that can catalyse O2-dependent formation of disulphide bonds. Erv2p transfers oxidizing equivalents to Pdi1p by a dithiol-disulphide exchange reaction, indicating that the Erv2p-dependent pathway for disulphide bond formation closely parallels that of the previously identified Ero1p-dependent pathway."xsd:string
http://purl.uniprot.org/citations/11584268http://purl.org/dc/terms/identifier"doi:10.1038/ncb1001-874"xsd:string
http://purl.uniprot.org/citations/11584268http://purl.org/dc/terms/identifier"doi:10.1038/ncb1001-874"xsd:string
http://purl.uniprot.org/citations/11584268http://purl.uniprot.org/core/author"Kaiser C.A."xsd:string
http://purl.uniprot.org/citations/11584268http://purl.uniprot.org/core/author"Kaiser C.A."xsd:string
http://purl.uniprot.org/citations/11584268http://purl.uniprot.org/core/author"Aaslund F."xsd:string
http://purl.uniprot.org/citations/11584268http://purl.uniprot.org/core/author"Aaslund F."xsd:string
http://purl.uniprot.org/citations/11584268http://purl.uniprot.org/core/author"Sevier C.S."xsd:string
http://purl.uniprot.org/citations/11584268http://purl.uniprot.org/core/author"Sevier C.S."xsd:string
http://purl.uniprot.org/citations/11584268http://purl.uniprot.org/core/author"Cuozzo J.W."xsd:string
http://purl.uniprot.org/citations/11584268http://purl.uniprot.org/core/author"Cuozzo J.W."xsd:string
http://purl.uniprot.org/citations/11584268http://purl.uniprot.org/core/author"Vala A."xsd:string
http://purl.uniprot.org/citations/11584268http://purl.uniprot.org/core/author"Vala A."xsd:string
http://purl.uniprot.org/citations/11584268http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11584268http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11584268http://purl.uniprot.org/core/name"Nat. Cell Biol."xsd:string
http://purl.uniprot.org/citations/11584268http://purl.uniprot.org/core/name"Nat. Cell Biol."xsd:string
http://purl.uniprot.org/citations/11584268http://purl.uniprot.org/core/pages"874-882"xsd:string
http://purl.uniprot.org/citations/11584268http://purl.uniprot.org/core/pages"874-882"xsd:string
http://purl.uniprot.org/citations/11584268http://purl.uniprot.org/core/title"A flavoprotein oxidase defines a new endoplasmic reticulum pathway for biosynthetic disulphide bond formation."xsd:string
http://purl.uniprot.org/citations/11584268http://purl.uniprot.org/core/title"A flavoprotein oxidase defines a new endoplasmic reticulum pathway for biosynthetic disulphide bond formation."xsd:string
http://purl.uniprot.org/citations/11584268http://purl.uniprot.org/core/volume"3"xsd:string