http://purl.uniprot.org/citations/11592043 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11592043 | http://www.w3.org/2000/01/rdf-schema#comment | "ObjectiveTo investigate the correlation between type 1 diabetes mellitus susceptibility and HLA-DPB1 and DQB1 genes in Shandong Han population.MethodsHLA-DPB1 and DQB1 genes analysis were performed by sequencing-based typing in 52 type 1 diabetes mellitus patients and 38 normal controls.ResultsThe frequency of DPB1*2201 in diabetics was significantly higher than that in controls(26.92% vs 5.26%, P<0.01), but the frequency of DPB1*0402 in diabetics was significantly lower than that in controls(11.54% vs 34.21%, P<0.01). The frequencies of DQB1*0201, *0303 and *0604 in diabetics were higher than those in controls (24.04% vs 10.53%, P< 0.01; 22.12% vs 6.58%, P<0.05; 19.23% vs 7.89%, P<0.05), while the frequency of DQB1*0301 in diabetics was significantly lower than that in controls (4.81% vs 25.00%, P<0.01).ConclusionDPB1*2201, DQB1*0201, *0303 and *0604 may be susceptible alleles, and DPB1*0402 and DQB1*0301 may be protective alleles in patients with type 1 diabetes mellitus."xsd:string |
http://purl.uniprot.org/citations/11592043 | http://purl.uniprot.org/core/author | "Zhang S."xsd:string |
http://purl.uniprot.org/citations/11592043 | http://purl.uniprot.org/core/author | "Yan H."xsd:string |
http://purl.uniprot.org/citations/11592043 | http://purl.uniprot.org/core/author | "Xing W."xsd:string |
http://purl.uniprot.org/citations/11592043 | http://purl.uniprot.org/core/author | "Jiang Z."xsd:string |
http://purl.uniprot.org/citations/11592043 | http://purl.uniprot.org/core/author | "Ke B."xsd:string |
http://purl.uniprot.org/citations/11592043 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11592043 | http://purl.uniprot.org/core/name | "Zhonghua Yi Xue Yi Chuan Xue Za Zhi"xsd:string |
http://purl.uniprot.org/citations/11592043 | http://purl.uniprot.org/core/pages | "362-365"xsd:string |
http://purl.uniprot.org/citations/11592043 | http://purl.uniprot.org/core/title | "[Sequencing-based typing of HLA-DPB1 and DQB1 exon 2 in patients with type 1 diabetes mellitus]."xsd:string |
http://purl.uniprot.org/citations/11592043 | http://purl.uniprot.org/core/volume | "18"xsd:string |
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