| http://purl.uniprot.org/citations/11601988 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11601988 | http://www.w3.org/2000/01/rdf-schema#comment | "To understand the mechanism involved in the coordination of the sequential repair reactions that lead to long-patch BER, we have investigated interactions between proteins involved in this pathway. We find that human AP endonuclease 1 (APE1) physically interacts with flap endonuclease 1 (FEN1) and with proliferating cell nuclear antigen. An oligonucleotide substrate containing a reduced abasic site, which was pre-incised with APE1, was employed to reconstitute the excision step of long-patch BER with purified human DNA polymerase beta and FEN1. We demonstrate that addition of APE1 to the excision reaction mixture slightly (1.5-2-fold) stimulates the removal of the displaced flap by FEN1. These results suggest the possibility that long-patch BER is coordinated and directed by protein-protein interactions."xsd:string |
| http://purl.uniprot.org/citations/11601988 | http://purl.org/dc/terms/identifier | "doi:10.1021/bi011117i"xsd:string |
| http://purl.uniprot.org/citations/11601988 | http://purl.uniprot.org/core/author | "Bohr V.A."xsd:string |
| http://purl.uniprot.org/citations/11601988 | http://purl.uniprot.org/core/author | "Dianov G.L."xsd:string |
| http://purl.uniprot.org/citations/11601988 | http://purl.uniprot.org/core/author | "Dianova I.I."xsd:string |
| http://purl.uniprot.org/citations/11601988 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11601988 | http://purl.uniprot.org/core/name | "Biochemistry"xsd:string |
| http://purl.uniprot.org/citations/11601988 | http://purl.uniprot.org/core/pages | "12639-12644"xsd:string |
| http://purl.uniprot.org/citations/11601988 | http://purl.uniprot.org/core/title | "Interaction of human AP endonuclease 1 with flap endonuclease 1 and proliferating cell nuclear antigen involved in long-patch base excision repair."xsd:string |
| http://purl.uniprot.org/citations/11601988 | http://purl.uniprot.org/core/volume | "40"xsd:string |
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| http://purl.uniprot.org/uniprot/#_Q07864-mappedCitation-11601988 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11601988 |
| http://purl.uniprot.org/uniprot/#_Q15054-mappedCitation-11601988 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11601988 |
| http://purl.uniprot.org/uniprot/#_A0A2S1WCK0-mappedCitation-11601988 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11601988 |
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| http://purl.uniprot.org/uniprot/#_B4DUA2-mappedCitation-11601988 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11601988 |
| http://purl.uniprot.org/uniprot/#_B4DWZ4-mappedCitation-11601988 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11601988 |
| http://purl.uniprot.org/uniprot/#_P49005-mappedCitation-11601988 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11601988 |
| http://purl.uniprot.org/uniprot/#_P15927-mappedCitation-11601988 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11601988 |
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