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http://purl.uniprot.org/citations/11602646http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11602646http://www.w3.org/2000/01/rdf-schema#comment"Given the broad expression of H-2 class Ib molecules on hematopoietic cells, antigen presentation pathways among CD1d expressing cells might tightly regulate CD1d-restricted natural killer T (NKT) cells. Bone marrow-derived dendritic cells (BM-DCs) and not adherent splenocytes become capable of triggering NK1.1(+)/T cell receptor (TCR)(int) hepatic NKT cell activation when (a) immature BM-DCs lack H-2D(b)-/-molecules or (b) BM-DCs undergo a stress signal of activation. In such conditions, BM-DCs promote T helper type 1 predominant CD1d-restricted NKT cell stimulation. H-2 class Ia-mediated inhibition involves more the direct H-2D(b) presentation than the indirect Qa-1(b) pathway. Such inhibition can be overruled by B7/CD28 interactions and marginally by CD40/CD40L or interleukin 12. These data point to a unique regulatory role of DCs in NKT cell innate immune responses and suggest that H-2 class Ia and Ib pathways differentially control NKT cell recognition of DC antigens."xsd:string
http://purl.uniprot.org/citations/11602646http://purl.org/dc/terms/identifier"doi:10.1084/jem.194.8.1179"xsd:string
http://purl.uniprot.org/citations/11602646http://purl.uniprot.org/core/author"Bendelac A."xsd:string
http://purl.uniprot.org/citations/11602646http://purl.uniprot.org/core/author"Tursz T."xsd:string
http://purl.uniprot.org/citations/11602646http://purl.uniprot.org/core/author"Wakasugi H."xsd:string
http://purl.uniprot.org/citations/11602646http://purl.uniprot.org/core/author"Terada M."xsd:string
http://purl.uniprot.org/citations/11602646http://purl.uniprot.org/core/author"Lemonnier F.A."xsd:string
http://purl.uniprot.org/citations/11602646http://purl.uniprot.org/core/author"Zitvogel L."xsd:string
http://purl.uniprot.org/citations/11602646http://purl.uniprot.org/core/author"Ikarashi Y."xsd:string
http://purl.uniprot.org/citations/11602646http://purl.uniprot.org/core/author"Mikami R."xsd:string
http://purl.uniprot.org/citations/11602646http://purl.uniprot.org/core/author"Angevin E."xsd:string
http://purl.uniprot.org/citations/11602646http://purl.uniprot.org/core/author"Chaput N."xsd:string
http://purl.uniprot.org/citations/11602646http://purl.uniprot.org/core/author"Terme M."xsd:string
http://purl.uniprot.org/citations/11602646http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11602646http://purl.uniprot.org/core/name"J Exp Med"xsd:string
http://purl.uniprot.org/citations/11602646http://purl.uniprot.org/core/pages"1179-1186"xsd:string
http://purl.uniprot.org/citations/11602646http://purl.uniprot.org/core/title"Dendritic cell maturation overrules H-2D-mediated natural killer T (NKT) cell inhibition: critical role for B7 in CD1d-dependent NKT cell interferon gamma production."xsd:string
http://purl.uniprot.org/citations/11602646http://purl.uniprot.org/core/volume"194"xsd:string
http://purl.uniprot.org/citations/11602646http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11602646
http://purl.uniprot.org/citations/11602646http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11602646
http://purl.uniprot.org/uniprot/#_A0A0B4J1G3-mappedCitation-11602646http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11602646
http://purl.uniprot.org/uniprot/#_A0A0R4J090-mappedCitation-11602646http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11602646
http://purl.uniprot.org/uniprot/#_K7WBQ4-mappedCitation-11602646http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11602646
http://purl.uniprot.org/uniprot/#_A0A482CGP7-mappedCitation-11602646http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11602646