| http://purl.uniprot.org/citations/11606068 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11606068 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11606068 | http://www.w3.org/2000/01/rdf-schema#comment | "Here we report the induction of gene expression of ABCG4, a member of the ABC transporter subfamily G, from human macrophages by oxysterols and retinoids, agonists of the nuclear receptors LXR and RXR. The cloned ABCG4 transcript has a size of 3.5 kb and contains an open reading frame which encodes a polypeptide of 646 amino acids. Structurally, the putative ABC transporter protein consists of a nucleotide binding fold followed by a cluster of six transmembrane-spanning domains and thus conforms to the group of half-size ABC transporters. Among the human ABC transporter subfamily G members the novel transporter shows highest protein sequence homology and identity to ABCG1 (84 and 72%, respectively). Analysis of the genomic organization demonstrates that the ABCG4 gene is composed of at least 14 exons which extend across a region of 12.6 kb in size on chromosome 11q23.3. Based on its structural features and an LXR/RXR-responsive regulation similar to the cellular lipid export protein ABCA1, we conclude that ABCG4 may be involved in macrophage lipid homeostasis."xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.2001.5756"xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.2001.5756"xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/author | "Rust S."xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/author | "Rust S."xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/author | "Assmann G."xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/author | "Assmann G."xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/author | "Cullen P."xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/author | "Cullen P."xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/author | "Lorkowski S."xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/author | "Lorkowski S."xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/author | "Berger G."xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/author | "Berger G."xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/author | "Engel T."xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/author | "Engel T."xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/author | "Lueken A."xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/author | "Lueken A."xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/author | "Schlueter B."xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/author | "Schlueter B."xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/11606068 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |