| http://purl.uniprot.org/citations/11684019 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11684019 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11684019 | http://www.w3.org/2000/01/rdf-schema#comment | "The efficient assembly of histone complexes and nucleosomes requires the participation of molecular chaperones. Currently, there is a paucity of data on their mechanism of action. We now present the structure of an N-terminal domain of nucleoplasmin (Np-core) at 2.3 A resolution. The Np-core monomer is an eight-stranded beta barrel that fits snugly within a stable pentamer. In the crystal, two pentamers associate to form a decamer. We show that both Np and Np-core are competent to assemble large complexes that contain the four core histones. Further experiments and modeling suggest that these complexes each contain five histone octamers which dock to a central Np decamer. This work has important ramifications for models of histone storage, sperm chromatin decondensation, and nucleosome assembly."xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(01)00354-9"xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(01)00354-9"xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/author | "Head J.F."xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/author | "Head J.F."xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/author | "Dutta S."xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/author | "Dutta S."xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/author | "Dingwall C."xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/author | "Dingwall C."xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/author | "Akey C.W."xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/author | "Akey C.W."xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/author | "Nolte R.T."xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/author | "Nolte R.T."xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/author | "Laue T."xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/author | "Laue T."xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/author | "Hartman K.L."xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/author | "Hartman K.L."xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/author | "Akey I.V."xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/author | "Akey I.V."xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/name | "Mol. Cell"xsd:string |
| http://purl.uniprot.org/citations/11684019 | http://purl.uniprot.org/core/name | "Mol. Cell"xsd:string |