| http://purl.uniprot.org/citations/11689009 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11689009 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11689009 | http://www.w3.org/2000/01/rdf-schema#comment | "Four structurally related peptides (pseudins 1-4) with antimicrobial activity were isolated from an extract of the skin of the paradoxical frog Pseudis paradoxa (Pseudidae). Pseudin-2 (GLNALKKVFQGIHEAIKLINNHVQ) was the most abundant peptide (22 nmol/g tissue) and also the most potent (minimum inhibitory concentrations, MIC = 2.5 microM against Escherichia coli, 80 microM against Staphylococcus aureus, and 130 microM against Candida albicans). The concentration of pseudin-2 producing 50% hemolysis of human erythrocytes was >300 microM. Circular dichroism studies showed that the pseudins belong to the class of cationic, amphipathic alpha-helical antimicrobial peptides but their amino acid sequences are not similar to any previously characterized peptides from frog skin. The pseudins do, however, show sequence similarity with a region at the C-terminus of DEFT, a death effector domain-containing protein expressed in mammalian testicular germ cells that is involved in the regulation of apoptosis."xsd:string |
| http://purl.uniprot.org/citations/11689009 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.2001.5884"xsd:string |
| http://purl.uniprot.org/citations/11689009 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.2001.5884"xsd:string |
| http://purl.uniprot.org/citations/11689009 | http://purl.uniprot.org/core/author | "Conlon J.M."xsd:string |
| http://purl.uniprot.org/citations/11689009 | http://purl.uniprot.org/core/author | "Conlon J.M."xsd:string |
| http://purl.uniprot.org/citations/11689009 | http://purl.uniprot.org/core/author | "Soto A.M."xsd:string |
| http://purl.uniprot.org/citations/11689009 | http://purl.uniprot.org/core/author | "Soto A.M."xsd:string |
| http://purl.uniprot.org/citations/11689009 | http://purl.uniprot.org/core/author | "Knoop F.C."xsd:string |
| http://purl.uniprot.org/citations/11689009 | http://purl.uniprot.org/core/author | "Knoop F.C."xsd:string |
| http://purl.uniprot.org/citations/11689009 | http://purl.uniprot.org/core/author | "Olson L. III"xsd:string |
| http://purl.uniprot.org/citations/11689009 | http://purl.uniprot.org/core/author | "Olson L. III"xsd:string |
| http://purl.uniprot.org/citations/11689009 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11689009 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11689009 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/11689009 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/11689009 | http://purl.uniprot.org/core/pages | "1001-1005"xsd:string |
| http://purl.uniprot.org/citations/11689009 | http://purl.uniprot.org/core/pages | "1001-1005"xsd:string |
| http://purl.uniprot.org/citations/11689009 | http://purl.uniprot.org/core/title | "Pseudin-2: an antimicrobial peptide with low hemolytic activity from the skin of the paradoxical frog."xsd:string |
| http://purl.uniprot.org/citations/11689009 | http://purl.uniprot.org/core/title | "Pseudin-2: an antimicrobial peptide with low hemolytic activity from the skin of the paradoxical frog."xsd:string |
| http://purl.uniprot.org/citations/11689009 | http://purl.uniprot.org/core/volume | "288"xsd:string |
| http://purl.uniprot.org/citations/11689009 | http://purl.uniprot.org/core/volume | "288"xsd:string |
| http://purl.uniprot.org/citations/11689009 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11689009 |
| http://purl.uniprot.org/citations/11689009 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11689009 |