| http://purl.uniprot.org/citations/11698390 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11698390 | http://www.w3.org/2000/01/rdf-schema#comment | "Increasing evidence suggests that alpha-synuclein is a common pathogenic molecule in several neurodegenerative diseases, particularly in Parkinson's disease. To understand alpha-synuclein pathology, we investigated molecules that interact with alpha-synuclein in human and rat brains and identified tubulin as an alpha-synuclein binding/associated protein. Tubulin co-localized with alpha-synuclein in Lewy bodies and other alpha-synuclein-positive pathological structures. Tubulin initiated and promoted alpha-synuclein fibril formation under physiological conditions in vitro. These findings suggest that an interaction between tubulin and alpha-synuclein might accelerate alpha-synuclein aggregation in diseased brains, leading to the formation of Lewy bodies."xsd:string |
| http://purl.uniprot.org/citations/11698390 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m102981200"xsd:string |
| http://purl.uniprot.org/citations/11698390 | http://purl.uniprot.org/core/author | "Nakamura M."xsd:string |
| http://purl.uniprot.org/citations/11698390 | http://purl.uniprot.org/core/author | "Shinoda T."xsd:string |
| http://purl.uniprot.org/citations/11698390 | http://purl.uniprot.org/core/author | "Ueda K."xsd:string |
| http://purl.uniprot.org/citations/11698390 | http://purl.uniprot.org/core/author | "Takeda K."xsd:string |
| http://purl.uniprot.org/citations/11698390 | http://purl.uniprot.org/core/author | "Hisanaga S."xsd:string |
| http://purl.uniprot.org/citations/11698390 | http://purl.uniprot.org/core/author | "Kaji H."xsd:string |
| http://purl.uniprot.org/citations/11698390 | http://purl.uniprot.org/core/author | "Arima K."xsd:string |
| http://purl.uniprot.org/citations/11698390 | http://purl.uniprot.org/core/author | "Hossain M.S."xsd:string |
| http://purl.uniprot.org/citations/11698390 | http://purl.uniprot.org/core/author | "Alim M.A."xsd:string |
| http://purl.uniprot.org/citations/11698390 | http://purl.uniprot.org/core/author | "Izumiyama Y."xsd:string |
| http://purl.uniprot.org/citations/11698390 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11698390 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/11698390 | http://purl.uniprot.org/core/pages | "2112-2117"xsd:string |
| http://purl.uniprot.org/citations/11698390 | http://purl.uniprot.org/core/title | "Tubulin seeds alpha-synuclein fibril formation."xsd:string |
| http://purl.uniprot.org/citations/11698390 | http://purl.uniprot.org/core/volume | "277"xsd:string |
| http://purl.uniprot.org/citations/11698390 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11698390 |
| http://purl.uniprot.org/citations/11698390 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11698390 |
| http://purl.uniprot.org/uniprot/P37840#attribution-2D7BDD4D215C2BCAF653F9A6F612B8A0 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/11698390 |
| http://purl.uniprot.org/uniprot/P37377#attribution-AAF7B9D2F347C34DAE16255CFABFFB8E | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/11698390 |
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| http://purl.uniprot.org/uniprot/#_A0A8I5ZKK9-mappedCitation-11698390 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11698390 |
| http://purl.uniprot.org/uniprot/#_P37377-mappedCitation-11698390 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11698390 |