| http://purl.uniprot.org/citations/11703826 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11703826 | http://www.w3.org/2000/01/rdf-schema#comment | "Behçet's disease (BD) is known to be associated with human leukocyte antigen (HLA) B51 in many different ethnic groups. An increased incidence of HLA-B51 in the patient group has also been reported in a Japanese population. Recently, the B51 antigen has been identified to comprise 21 alleles, B*5101-B*5121. Further, not only HLA-B*5101 but also HLA-B*5108 were found to be relatively increased in the patient groups among Italian and Saudi Arabian populations. Therefore, we performed HLA-B*51 allele genotyping by the polymerase chain reaction-sequencing based typing (PCR-SBT) method in order to investigate whether there is any correlation of one particular B51-associated allele with Japanese BD. Ninety-six Japanese patients with BD and 132 healthy Japanese volunteers were enrolled in this study. As a result, the phenotype frequency of the B51 antigen was confirmed to be remarkably increased in the patient group as compared to the ethnically matched control group (59.4% in patients vs. 13.6% in controls; Pc=0.0000000000098, R.R.=9.3). In the B*51 allele genotyping, 56 out of 57 B51-positive patients were defined as B*5101 and the remaining one was B*5102. In contrast, all of 18 B51-positive normal controls were B*5101. None of the Japanese patients and healthy controls carried the HLA-B*5108 allele. This study revealed that B*51 allelic distribution in Japanese was different from those in Italian and Saudi Arabian populations, and that the significantly high incidence of the HLA-B51 antigen in the Japanese BD patient group was mostly caused by the significant increase of the HLA-B*5101 allele."xsd:string |
| http://purl.uniprot.org/citations/11703826 | http://purl.org/dc/terms/identifier | "doi:10.1034/j.1399-0039.2001.580306.x"xsd:string |
| http://purl.uniprot.org/citations/11703826 | http://purl.uniprot.org/core/author | "Inoko H."xsd:string |
| http://purl.uniprot.org/citations/11703826 | http://purl.uniprot.org/core/author | "Ohno S."xsd:string |
| http://purl.uniprot.org/citations/11703826 | http://purl.uniprot.org/core/author | "Shiina T."xsd:string |
| http://purl.uniprot.org/citations/11703826 | http://purl.uniprot.org/core/author | "Katsuyama Y."xsd:string |
| http://purl.uniprot.org/citations/11703826 | http://purl.uniprot.org/core/author | "Ando H."xsd:string |
| http://purl.uniprot.org/citations/11703826 | http://purl.uniprot.org/core/author | "Ota M."xsd:string |
| http://purl.uniprot.org/citations/11703826 | http://purl.uniprot.org/core/author | "Yabuki K."xsd:string |
| http://purl.uniprot.org/citations/11703826 | http://purl.uniprot.org/core/author | "Mizuki N."xsd:string |
| http://purl.uniprot.org/citations/11703826 | http://purl.uniprot.org/core/author | "Nomura E."xsd:string |
| http://purl.uniprot.org/citations/11703826 | http://purl.uniprot.org/core/author | "Onari K."xsd:string |
| http://purl.uniprot.org/citations/11703826 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11703826 | http://purl.uniprot.org/core/name | "Tissue Antigens"xsd:string |
| http://purl.uniprot.org/citations/11703826 | http://purl.uniprot.org/core/pages | "181-184"xsd:string |
| http://purl.uniprot.org/citations/11703826 | http://purl.uniprot.org/core/title | "HLA-B*51 allele analysis by the PCR-SBT method and a strong association of HLA-B*5101 with Japanese patients with Behcet's disease."xsd:string |
| http://purl.uniprot.org/citations/11703826 | http://purl.uniprot.org/core/volume | "58"xsd:string |
| http://purl.uniprot.org/citations/11703826 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11703826 |
| http://purl.uniprot.org/citations/11703826 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11703826 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C552-mappedCitation-11703826 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11703826 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DC98-mappedCitation-11703826 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11703826 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DCA0-mappedCitation-11703826 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11703826 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DCA1-mappedCitation-11703826 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11703826 |
| http://purl.uniprot.org/uniprot/#_A0A068B107-mappedCitation-11703826 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11703826 |