http://purl.uniprot.org/citations/11703931 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11703931 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11703931 | http://www.w3.org/2000/01/rdf-schema#comment | "How the occupied KDEL receptor ERD2 is sorted into COPI vesicles for Golgi-to-ER transport is largely unknown. Here, interactions between proteins of the COPI transport machinery occurring during a "wave" of transport of a KDEL ligand were studied in living cells. FRET between CFP and YFP fusion proteins was measured by multifocal multiphoton microscopy and bulk-cell spectrofluorimetry. Ligand binding induces oligomerization of ERD2 and recruitment of ARFGAP to the Golgi, where the (ERD2)n/ARFGAP complex interacts with membrane-bound ARF1. During KDEL ligand transport, interactions of ERD2 with beta-COP and p23 decrease and the proteins segregate. Both p24a and p23 interact with ARF1, but only p24 interacts with ARFGAP. These findings suggest a model for how cargo-induced oligomerization of ERD2 regulates its sorting into COPI-coated buds."xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1534-5807(01)00004-1"xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1534-5807(01)00004-1"xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/author | "Straub M."xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/author | "Straub M."xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/author | "Duden R."xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/author | "Duden R."xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/author | "Hell S.W."xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/author | "Hell S.W."xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/author | "Majoul I."xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/author | "Majoul I."xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/author | "Soling H.D."xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/author | "Soling H.D."xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/name | "Dev. Cell"xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/name | "Dev. Cell"xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/pages | "139-153"xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/pages | "139-153"xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/title | "KDEL-cargo regulates interactions between proteins involved in COPI vesicle traffic: measurements in living cells using FRET."xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/title | "KDEL-cargo regulates interactions between proteins involved in COPI vesicle traffic: measurements in living cells using FRET."xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/volume | "1"xsd:string |
http://purl.uniprot.org/citations/11703931 | http://purl.uniprot.org/core/volume | "1"xsd:string |