http://purl.uniprot.org/citations/11704680 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11704680 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11704680 | http://www.w3.org/2000/01/rdf-schema#comment | "Transcriptional coactivators either bridge transcription factors and the components of the basal transcription apparatus and/or remodel the chromatin structures. We isolated a novel nuclear protein based on its interaction with the recently described general coactivator activating signal cointegrator-2 (ASC-2). This protein CAPER (for coactivator of activating protein-1 (AP-1) and estrogen receptors (ERs)) selectively bound, among the many transcription factors we tested, the AP-1 component c-Jun and the estradiol-bound ligand binding domains of ERalpha and ERbeta. Interestingly, CAPER exhibited a cryptic autonomous transactivation function that becomes activated only in the presence of estradiol-bound ER. In cotransfections, CAPER stimulated transactivation by ERalpha, ERbeta, and AP-1. Thus, CAPER may represent a more selective transcriptional coactivator molecule that plays a pivotal role for the function of AP-1 and ERs in vivo in conjunction with the general coactivator ASC-2."xsd:string |
http://purl.uniprot.org/citations/11704680 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m110417200"xsd:string |
http://purl.uniprot.org/citations/11704680 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m110417200"xsd:string |
http://purl.uniprot.org/citations/11704680 | http://purl.uniprot.org/core/author | "Lee J.W."xsd:string |
http://purl.uniprot.org/citations/11704680 | http://purl.uniprot.org/core/author | "Lee J.W."xsd:string |
http://purl.uniprot.org/citations/11704680 | http://purl.uniprot.org/core/author | "Jung D.-J."xsd:string |
http://purl.uniprot.org/citations/11704680 | http://purl.uniprot.org/core/author | "Jung D.-J."xsd:string |
http://purl.uniprot.org/citations/11704680 | http://purl.uniprot.org/core/author | "Na S.-Y."xsd:string |
http://purl.uniprot.org/citations/11704680 | http://purl.uniprot.org/core/author | "Na S.-Y."xsd:string |
http://purl.uniprot.org/citations/11704680 | http://purl.uniprot.org/core/author | "Na D.S."xsd:string |
http://purl.uniprot.org/citations/11704680 | http://purl.uniprot.org/core/author | "Na D.S."xsd:string |
http://purl.uniprot.org/citations/11704680 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/11704680 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/11704680 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/11704680 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/11704680 | http://purl.uniprot.org/core/pages | "1229-1234"xsd:string |
http://purl.uniprot.org/citations/11704680 | http://purl.uniprot.org/core/pages | "1229-1234"xsd:string |
http://purl.uniprot.org/citations/11704680 | http://purl.uniprot.org/core/title | "Molecular cloning and characterization of CAPER, a novel coactivator of activating protein-1 and estrogen receptors."xsd:string |
http://purl.uniprot.org/citations/11704680 | http://purl.uniprot.org/core/title | "Molecular cloning and characterization of CAPER, a novel coactivator of activating protein-1 and estrogen receptors."xsd:string |
http://purl.uniprot.org/citations/11704680 | http://purl.uniprot.org/core/volume | "277"xsd:string |
http://purl.uniprot.org/citations/11704680 | http://purl.uniprot.org/core/volume | "277"xsd:string |
http://purl.uniprot.org/citations/11704680 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11704680 |
http://purl.uniprot.org/citations/11704680 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11704680 |