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http://purl.uniprot.org/citations/11704680http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11704680http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11704680http://www.w3.org/2000/01/rdf-schema#comment"Transcriptional coactivators either bridge transcription factors and the components of the basal transcription apparatus and/or remodel the chromatin structures. We isolated a novel nuclear protein based on its interaction with the recently described general coactivator activating signal cointegrator-2 (ASC-2). This protein CAPER (for coactivator of activating protein-1 (AP-1) and estrogen receptors (ERs)) selectively bound, among the many transcription factors we tested, the AP-1 component c-Jun and the estradiol-bound ligand binding domains of ERalpha and ERbeta. Interestingly, CAPER exhibited a cryptic autonomous transactivation function that becomes activated only in the presence of estradiol-bound ER. In cotransfections, CAPER stimulated transactivation by ERalpha, ERbeta, and AP-1. Thus, CAPER may represent a more selective transcriptional coactivator molecule that plays a pivotal role for the function of AP-1 and ERs in vivo in conjunction with the general coactivator ASC-2."xsd:string
http://purl.uniprot.org/citations/11704680http://purl.org/dc/terms/identifier"doi:10.1074/jbc.m110417200"xsd:string
http://purl.uniprot.org/citations/11704680http://purl.org/dc/terms/identifier"doi:10.1074/jbc.m110417200"xsd:string
http://purl.uniprot.org/citations/11704680http://purl.uniprot.org/core/author"Lee J.W."xsd:string
http://purl.uniprot.org/citations/11704680http://purl.uniprot.org/core/author"Lee J.W."xsd:string
http://purl.uniprot.org/citations/11704680http://purl.uniprot.org/core/author"Jung D.-J."xsd:string
http://purl.uniprot.org/citations/11704680http://purl.uniprot.org/core/author"Jung D.-J."xsd:string
http://purl.uniprot.org/citations/11704680http://purl.uniprot.org/core/author"Na S.-Y."xsd:string
http://purl.uniprot.org/citations/11704680http://purl.uniprot.org/core/author"Na S.-Y."xsd:string
http://purl.uniprot.org/citations/11704680http://purl.uniprot.org/core/author"Na D.S."xsd:string
http://purl.uniprot.org/citations/11704680http://purl.uniprot.org/core/author"Na D.S."xsd:string
http://purl.uniprot.org/citations/11704680http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/11704680http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/11704680http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/11704680http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/11704680http://purl.uniprot.org/core/pages"1229-1234"xsd:string
http://purl.uniprot.org/citations/11704680http://purl.uniprot.org/core/pages"1229-1234"xsd:string
http://purl.uniprot.org/citations/11704680http://purl.uniprot.org/core/title"Molecular cloning and characterization of CAPER, a novel coactivator of activating protein-1 and estrogen receptors."xsd:string
http://purl.uniprot.org/citations/11704680http://purl.uniprot.org/core/title"Molecular cloning and characterization of CAPER, a novel coactivator of activating protein-1 and estrogen receptors."xsd:string
http://purl.uniprot.org/citations/11704680http://purl.uniprot.org/core/volume"277"xsd:string
http://purl.uniprot.org/citations/11704680http://purl.uniprot.org/core/volume"277"xsd:string
http://purl.uniprot.org/citations/11704680http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11704680
http://purl.uniprot.org/citations/11704680http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11704680