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http://purl.uniprot.org/citations/11715513http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11715513http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11715513http://www.w3.org/2000/01/rdf-schema#comment"

Objective

To study the correction phenotype of temperature sensitive mutant rad24LR of S. cerevisiae and to clone wild human functional homologue.

Methods

The temperature sensitive mutant rad24LR was studied by complementation test. Transformation of rad24LR was performed with human cDNA expression library to screen for reversion phenotype.

Results

RAD24L can complement the radiation sensitive phenotype of the mutation. Its homologue of human cDNA was cloned by screening transformed rad24LR with human expression library for reversion phenotype.

Conclusion

Human DNA repair gene hR24L was successfully cloned in this study. The product hR24L is involved in both DNA excision repair and recombination repair."xsd:string
http://purl.uniprot.org/citations/11715513http://purl.uniprot.org/core/author"Han Y."xsd:string
http://purl.uniprot.org/citations/11715513http://purl.uniprot.org/core/author"Han Y."xsd:string
http://purl.uniprot.org/citations/11715513http://purl.uniprot.org/core/author"Zhu Y."xsd:string
http://purl.uniprot.org/citations/11715513http://purl.uniprot.org/core/author"Zhu Y."xsd:string
http://purl.uniprot.org/citations/11715513http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/11715513http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/11715513http://purl.uniprot.org/core/name"Zhonghua Yi Xue Za Zhi"xsd:string
http://purl.uniprot.org/citations/11715513http://purl.uniprot.org/core/name"Zhonghua Yi Xue Za Zhi"xsd:string
http://purl.uniprot.org/citations/11715513http://purl.uniprot.org/core/pages"941-943"xsd:string
http://purl.uniprot.org/citations/11715513http://purl.uniprot.org/core/pages"941-943"xsd:string
http://purl.uniprot.org/citations/11715513http://purl.uniprot.org/core/title"Human hR24L gene is involved in DNA excision repair and recombination repair."xsd:string
http://purl.uniprot.org/citations/11715513http://purl.uniprot.org/core/title"Human hR24L gene is involved in DNA excision repair and recombination repair."xsd:string
http://purl.uniprot.org/citations/11715513http://purl.uniprot.org/core/volume"79"xsd:string
http://purl.uniprot.org/citations/11715513http://purl.uniprot.org/core/volume"79"xsd:string
http://purl.uniprot.org/citations/11715513http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11715513
http://purl.uniprot.org/citations/11715513http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11715513
http://purl.uniprot.org/citations/11715513http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11715513
http://purl.uniprot.org/citations/11715513http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11715513
http://purl.uniprot.org/uniprot/O75943http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/11715513
http://purl.uniprot.org/uniprot/#_kb.O75943_up.isolatedFrom_tissue.564http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/11715513
http://purl.uniprot.org/uniprot/O75943#attribution-CFE5252F6F32778860357F1967746C73http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/11715513
http://purl.uniprot.org/uniprot/#_O75943-citation-11715513http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11715513