| http://purl.uniprot.org/citations/11717445 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11717445 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11717445 | http://www.w3.org/2000/01/rdf-schema#comment | "A role for caspase-10, previously implicated in the autoimmune lymphoproliferative syndrome, in death receptor signaling has not been directly shown. Here we show that caspase-10 can function independently of caspase-8 in initiating Fas- and tumor necrosis factor-related apoptosis-inducing ligand-receptor-mediated apoptosis. Moreover, Fas crosslinking in primary human T cells leads to the recruitment and activation of caspase-10. Fluorescent resonance energy transfer analysis indicates that the death-effector domains of caspase-8 and -10 both interact with the death-effector domain of FADD. Nonetheless, we find that caspase-8 and -10 may have different apoptosis substrates and therefore potentially distinct roles in death receptor signaling or other cellular processes."xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.241358198"xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.241358198"xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/author | "Wang J."xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/author | "Wang J."xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/author | "Wong W."xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/author | "Wong W."xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/author | "Lenardo M.J."xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/author | "Lenardo M.J."xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/author | "Chun H.J."xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/author | "Chun H.J."xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/author | "Spencer D.M."xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/author | "Spencer D.M."xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/pages | "13884-13888"xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/pages | "13884-13888"xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/title | "Caspase-10 is an initiator caspase in death receptor signaling."xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/title | "Caspase-10 is an initiator caspase in death receptor signaling."xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/volume | "98"xsd:string |
| http://purl.uniprot.org/citations/11717445 | http://purl.uniprot.org/core/volume | "98"xsd:string |