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http://purl.uniprot.org/citations/11720865 | http://www.w3.org/2000/01/rdf-schema#comment | "Peptidomimetic inhibitors of thrombin lacking the important Ser195-carbonyl interaction have been prepared. The binding energy lost after the removal of the activated carbonyl was recaptured through a series of modifications of the P1 residues of the bicyclic lactam inhibitors. Selected substituted compounds displayed useful pharmacological profiles both in vitro and in vivo."xsd:string |
http://purl.uniprot.org/citations/11720865 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0960-894x(01)00661-8"xsd:string |
http://purl.uniprot.org/citations/11720865 | http://purl.uniprot.org/core/author | "Siddiqui M.A."xsd:string |
http://purl.uniprot.org/citations/11720865 | http://purl.uniprot.org/core/author | "Levesque S."xsd:string |
http://purl.uniprot.org/citations/11720865 | http://purl.uniprot.org/core/author | "Rubin J.R."xsd:string |
http://purl.uniprot.org/citations/11720865 | http://purl.uniprot.org/core/author | "Bachand B."xsd:string |
http://purl.uniprot.org/citations/11720865 | http://purl.uniprot.org/core/author | "Edmunds J.J."xsd:string |
http://purl.uniprot.org/citations/11720865 | http://purl.uniprot.org/core/author | "Leblond L."xsd:string |
http://purl.uniprot.org/citations/11720865 | http://purl.uniprot.org/core/author | "St-Denis Y."xsd:string |
http://purl.uniprot.org/citations/11720865 | http://purl.uniprot.org/core/author | "Winocour P.D."xsd:string |
http://purl.uniprot.org/citations/11720865 | http://purl.uniprot.org/core/author | "Preville P."xsd:string |
http://purl.uniprot.org/citations/11720865 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11720865 | http://purl.uniprot.org/core/name | "Bioorg Med Chem Lett"xsd:string |
http://purl.uniprot.org/citations/11720865 | http://purl.uniprot.org/core/pages | "3161-3164"xsd:string |
http://purl.uniprot.org/citations/11720865 | http://purl.uniprot.org/core/title | "Novel bicyclic lactam inhibitors of thrombin: potency and selectivity optimization through P1 residues."xsd:string |
http://purl.uniprot.org/citations/11720865 | http://purl.uniprot.org/core/volume | "11"xsd:string |
http://purl.uniprot.org/citations/11720865 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11720865 |
http://purl.uniprot.org/citations/11720865 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11720865 |
http://purl.uniprot.org/uniprot/#_P00734-mappedCitation-11720865 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11720865 |
http://purl.uniprot.org/uniprot/P00734 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/11720865 |