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http://purl.uniprot.org/citations/11738026http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11738026http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11738026http://www.w3.org/2000/01/rdf-schema#comment"Transport of synaptic components is a regulated process. Loss-of-function mutations in the C. elegans unc-16 gene result in the mislocalization of synaptic vesicle and glutamate receptor markers. unc-16 encodes a homolog of mouse JSAP1/JIP3 and Drosophila Sunday Driver. Like JSAP1/JIP3, UNC-16 physically interacts with JNK and JNK kinases. Deletion mutations in Caenorhabditis elegans JNK and JNK kinases result in similar mislocalization of synaptic vesicle markers and enhance weak unc-16 mutant phenotypes. unc-116 kinesin heavy chain mutants also mislocalize synaptic vesicle markers, as well as a functional UNC-16::GFP. Intriguingly, unc-16 mutations partially suppress the vesicle retention defect in unc-104 KIF1A kinesin mutants. Our results suggest that UNC-16 may regulate the localization of vesicular cargo by integrating JNK signaling and kinesin-1 transport."xsd:string
http://purl.uniprot.org/citations/11738026http://purl.org/dc/terms/identifier"doi:10.1016/s0896-6273(01)00532-3"xsd:string
http://purl.uniprot.org/citations/11738026http://purl.org/dc/terms/identifier"doi:10.1016/s0896-6273(01)00532-3"xsd:string
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/author"Jin Y."xsd:string
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/author"Jin Y."xsd:string
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/author"Matsumoto K."xsd:string
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/author"Matsumoto K."xsd:string
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/author"Kawasaki M."xsd:string
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/author"Kawasaki M."xsd:string
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/author"Hisamoto N."xsd:string
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/author"Hisamoto N."xsd:string
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/author"Byrd D.T."xsd:string
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/author"Byrd D.T."xsd:string
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/author"Walcoff M."xsd:string
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/author"Walcoff M."xsd:string
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/name"Neuron"xsd:string
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/name"Neuron"xsd:string
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/pages"787-800"xsd:string
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/pages"787-800"xsd:string
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/title"UNC-16, a JNK-signaling scaffold protein, regulates vesicle transport in C. elegans."xsd:string
http://purl.uniprot.org/citations/11738026http://purl.uniprot.org/core/title"UNC-16, a JNK-signaling scaffold protein, regulates vesicle transport in C. elegans."xsd:string