| http://purl.uniprot.org/citations/11748357 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11748357 | http://www.w3.org/2000/01/rdf-schema#comment | "The purpose of this study was to examine whether there are the associations between TNF alpha and TNF beta gene polymorphisms and the development and progression of Ig A nephropathy (IgAN). A cross-sectional study on TNF alpha and TNF betagene polymorphisms by polymerase chain reaction with restriction fragment length poly-morphisms was performed on 76 patients with primary IgAN confirmed by renal biopsy and 100 healthy controls. The allele with G-->A substitution was designated as TNFA2 for the TNF alpha gene and TNFB2 for the TNF betagene. A patient in whom dialysis treatment was started or whose serum creatinine became double or over during the follow-up duration was designated as a "progressor". The TNFA2/ TNFA2 genotype was more prevalent in the progressor than in the non-pregressor group (20.0 vs 3.3%, p<0.05). Clinical factors such as serum creatinine, systolic and diastolic blood pressure (p<0.001, respectively) were higher and pathologic factor such as Grade IV or V renal lesions was more prevalent (p<0.01) in the progressor than in the non-progressor group. Therefore, TNFA2/TNFA2 genotype may be a risk factor for the progression of IgAN."xsd:string |
| http://purl.uniprot.org/citations/11748357 | http://purl.org/dc/terms/identifier | "doi:10.3346/jkms.2001.16.6.751"xsd:string |
| http://purl.uniprot.org/citations/11748357 | http://purl.uniprot.org/core/author | "Hwang K.Y."xsd:string |
| http://purl.uniprot.org/citations/11748357 | http://purl.uniprot.org/core/author | "Hong S.Y."xsd:string |
| http://purl.uniprot.org/citations/11748357 | http://purl.uniprot.org/core/author | "Lee E.Y."xsd:string |
| http://purl.uniprot.org/citations/11748357 | http://purl.uniprot.org/core/author | "Yang D.H."xsd:string |
| http://purl.uniprot.org/citations/11748357 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11748357 | http://purl.uniprot.org/core/name | "J Korean Med Sci"xsd:string |
| http://purl.uniprot.org/citations/11748357 | http://purl.uniprot.org/core/pages | "751-755"xsd:string |
| http://purl.uniprot.org/citations/11748357 | http://purl.uniprot.org/core/title | "Is tumor necrosis factor genotype (TNFA2/TNFA2)a genetic prognostic factor of an unfavorable outcome in IgA nephropathy?"xsd:string |
| http://purl.uniprot.org/citations/11748357 | http://purl.uniprot.org/core/volume | "16"xsd:string |
| http://purl.uniprot.org/citations/11748357 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11748357 |
| http://purl.uniprot.org/citations/11748357 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11748357 |
| http://purl.uniprot.org/uniprot/#_A0A0G2YPN5-mappedCitation-11748357 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11748357 |
| http://purl.uniprot.org/uniprot/#_B3KSL2-mappedCitation-11748357 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11748357 |
| http://purl.uniprot.org/uniprot/#_A0A161I202-mappedCitation-11748357 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11748357 |
| http://purl.uniprot.org/uniprot/#_A0A1U9X8M9-mappedCitation-11748357 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11748357 |
| http://purl.uniprot.org/uniprot/#_A0A411D318-mappedCitation-11748357 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11748357 |
| http://purl.uniprot.org/uniprot/#_A0A510GFL8-mappedCitation-11748357 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11748357 |
| http://purl.uniprot.org/uniprot/#_C1K3N5-mappedCitation-11748357 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11748357 |
| http://purl.uniprot.org/uniprot/#_B5BUQ6-mappedCitation-11748357 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11748357 |
| http://purl.uniprot.org/uniprot/#_A0A977WMN2-mappedCitation-11748357 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11748357 |
| http://purl.uniprot.org/uniprot/#_A8K494-mappedCitation-11748357 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11748357 |
| http://purl.uniprot.org/uniprot/#_B4E1V0-mappedCitation-11748357 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11748357 |