http://purl.uniprot.org/citations/11755530 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11755530 | http://www.w3.org/2000/01/rdf-schema#comment | "Neurotrophins support neuronal survival, development, and plasticity through processes requiring gene expression. We studied how vgf target gene transcription is mediated by a critical promoter region containing E-box, CCAAT and cAMP response element (CRE) sites. The p300 acetylase was present in two distinct protein complexes bound to this region. One complex, containing HEB (ubiquitous basic helix-loop-helix (bHLH)), bound the promoter in non-neuronal cells and was involved in repressing vgf expression. Neurotrophin-dependent transcription was mediated by the second complex, specific for neuronal cells, which included CRE binding protein and MASH1 (neuro-specific bHLH), bound the CCAAT motif, and was target of neurotrophin signalling. The interaction, mediated by p300, of different transcription factors may add specificity to the neurotrophin response."xsd:string |
http://purl.uniprot.org/citations/11755530 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(01)03227-6"xsd:string |
http://purl.uniprot.org/citations/11755530 | http://purl.uniprot.org/core/author | "Gargano S."xsd:string |
http://purl.uniprot.org/citations/11755530 | http://purl.uniprot.org/core/author | "Mandolesi G."xsd:string |
http://purl.uniprot.org/citations/11755530 | http://purl.uniprot.org/core/author | "Levi A."xsd:string |
http://purl.uniprot.org/citations/11755530 | http://purl.uniprot.org/core/author | "Mosca L."xsd:string |
http://purl.uniprot.org/citations/11755530 | http://purl.uniprot.org/core/author | "Illi B."xsd:string |
http://purl.uniprot.org/citations/11755530 | http://purl.uniprot.org/core/author | "Jucker R."xsd:string |
http://purl.uniprot.org/citations/11755530 | http://purl.uniprot.org/core/author | "Nasi S."xsd:string |
http://purl.uniprot.org/citations/11755530 | http://purl.uniprot.org/core/author | "Pennuto M."xsd:string |
http://purl.uniprot.org/citations/11755530 | http://purl.uniprot.org/core/author | "Molfetta R."xsd:string |
http://purl.uniprot.org/citations/11755530 | http://purl.uniprot.org/core/author | "Soucek L."xsd:string |
http://purl.uniprot.org/citations/11755530 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/11755530 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/11755530 | http://purl.uniprot.org/core/pages | "50-56"xsd:string |
http://purl.uniprot.org/citations/11755530 | http://purl.uniprot.org/core/title | "NGF-dependent and tissue-specific transcription of vgf is regulated by a CREB-p300 and bHLH factor interaction."xsd:string |
http://purl.uniprot.org/citations/11755530 | http://purl.uniprot.org/core/volume | "510"xsd:string |
http://purl.uniprot.org/citations/11755530 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11755530 |
http://purl.uniprot.org/citations/11755530 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11755530 |
http://purl.uniprot.org/uniprot/Q5RJS0#attribution-F9D6C822ECFEABDF0B7DEAE744B8395C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/11755530 |
http://purl.uniprot.org/uniprot/A6HT04#attribution-F9D6C822ECFEABDF0B7DEAE744B8395C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/11755530 |
http://purl.uniprot.org/uniprot/A0A0G2QC09#attribution-F9D6C822ECFEABDF0B7DEAE744B8395C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/11755530 |
http://purl.uniprot.org/uniprot/A0A8I6G641#attribution-F9D6C822ECFEABDF0B7DEAE744B8395C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/11755530 |
http://purl.uniprot.org/uniprot/A6HT05#attribution-F9D6C822ECFEABDF0B7DEAE744B8395C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/11755530 |