| http://purl.uniprot.org/citations/11779479 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11779479 | http://www.w3.org/2000/01/rdf-schema#comment | "Slit proteins have previously been shown to regulate axon guidance, branching, and neural migration. Here we report that, in addition to acting as a chemorepellant for cortical axons, Slit1 regulates dendritic development. Slit1 is expressed in the developing cortex, and exposure to Slit1 leads to increased dendritic growth and branching. Conversely, inhibition of Slit-Robo interactions by Robo-Fc fusion proteins or by a dominant-negative Robo attenuates dendritic branching. Stimulation of neurons transfected with a Met-Robo chimeric receptor with Hepatocyte growth factor leads to a robust induction of dendritic growth and branching, suggesting that Robo-mediated signaling is sufficient to induce dendritic remodeling. These experiments indicate that Slit-Robo interactions may exert a significant influence over the specification of cortical neuron morphology by regulating both axon guidance and dendritic patterning."xsd:string |
| http://purl.uniprot.org/citations/11779479 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0896-6273(01)00566-9"xsd:string |
| http://purl.uniprot.org/citations/11779479 | http://purl.uniprot.org/core/author | "Ghosh A."xsd:string |
| http://purl.uniprot.org/citations/11779479 | http://purl.uniprot.org/core/author | "Goodman C.S."xsd:string |
| http://purl.uniprot.org/citations/11779479 | http://purl.uniprot.org/core/author | "Tessier-Lavigne M."xsd:string |
| http://purl.uniprot.org/citations/11779479 | http://purl.uniprot.org/core/author | "Stein E."xsd:string |
| http://purl.uniprot.org/citations/11779479 | http://purl.uniprot.org/core/author | "Chedotal A."xsd:string |
| http://purl.uniprot.org/citations/11779479 | http://purl.uniprot.org/core/author | "Marillat V."xsd:string |
| http://purl.uniprot.org/citations/11779479 | http://purl.uniprot.org/core/author | "Whitford K.L."xsd:string |
| http://purl.uniprot.org/citations/11779479 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11779479 | http://purl.uniprot.org/core/name | "Neuron"xsd:string |
| http://purl.uniprot.org/citations/11779479 | http://purl.uniprot.org/core/pages | "47-61"xsd:string |
| http://purl.uniprot.org/citations/11779479 | http://purl.uniprot.org/core/title | "Regulation of cortical dendrite development by Slit-Robo interactions."xsd:string |
| http://purl.uniprot.org/citations/11779479 | http://purl.uniprot.org/core/volume | "33"xsd:string |
| http://purl.uniprot.org/citations/11779479 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11779479 |
| http://purl.uniprot.org/citations/11779479 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11779479 |
| http://purl.uniprot.org/uniprot/O55005#attribution-E0B804F3D811CE56DE1717A51B45F7AF | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/11779479 |
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