http://purl.uniprot.org/citations/11782431 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11782431 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11782431 | http://www.w3.org/2000/01/rdf-schema#comment | "CDO is a cell surface receptor-like protein that positively regulates myogenic differentiation. Reported here is the identification of BOC, which, with CDO, defines a newly recognized subfamily within the immunoglobulin superfamily. cdo and boc are co-expressed in muscle precursors in the developing mouse embryo. Like CDO, BOC accelerates differentiation of cultured myoblast cell lines and participates in a positive feedback loop with the myogenic transcription factor, MyoD. CDO and BOC form complexes in a cis fashion via association of both their ectodomains and their intracellular domains. A soluble fusion protein that contains the entire BOC ectodomain functions similarly to full-length BOC to promote myogenic differentiation, indicating that the intracellular region is dispensable for its activity in this system. Furthermore, a dominant-negative form of CDO inhibits the pro-myogenic effects of soluble BOC, suggesting that BOC is dependent on CDO for its activity. CDO and BOC are proposed to be components of a receptor complex that mediates some of the cell-cell interactions between muscle precursors that are required for myogenesis."xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.org/dc/terms/identifier | "doi:10.1093/emboj/21.1.114"xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.org/dc/terms/identifier | "doi:10.1093/emboj/21.1.114"xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/author | "Hu Y."xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/author | "Hu Y."xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/author | "Kang J.S."xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/author | "Kang J.-S."xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/author | "Kang J.-S."xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/author | "Krauss R.S."xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/author | "Krauss R.S."xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/author | "Mulieri P.J."xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/author | "Mulieri P.J."xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/author | "Taliana L."xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/author | "Taliana L."xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/pages | "114-124"xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/pages | "114-124"xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/title | "BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation."xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/title | "BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation."xsd:string |
http://purl.uniprot.org/citations/11782431 | http://purl.uniprot.org/core/volume | "21"xsd:string |