| http://purl.uniprot.org/citations/11784104 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11784104 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11784104 | http://www.w3.org/2000/01/rdf-schema#comment | "The proportions of prespore and prestalk cells in Dictyostelium discoideum are regulated so that they are size invariant and can adjust when the ratio is perturbed. We have found that disruption of the gene amdA that encodes AMP deaminase results in a significantly increased proportion of prestalk cells. Strains lacking AMP deaminase form short, thick stalks and glassy sori with less than 5% the normal number of spores. The levels of prestalk-specific mRNAs in amdA(-) cells are more than twice as high as those in wild-type strains and prespore-specific mRNAs are reduced. Using an ecmA::lacZ construct to mark prestalk cells, we found that amdA(-) null slugs have twice the normal number of prestalk cells. The number of cells expressing an ecmO::lacZ construct was not affected by loss of AmdA, indicating that the mutation results in an increase in PST-A prestalk cells rather than PST-O cells. This alteration in cell-type proportioning is a cell-autonomous consequence of the loss of AMP deaminase since mutant cells developed together with wild-type cells still produced excess prestalk cells and wild-type cells carrying the ecmA::lacZ construct formed normal numbers of prestalk cells when developed together with an equal number of amdA(-) mutant cells."xsd:string |
| http://purl.uniprot.org/citations/11784104 | http://purl.org/dc/terms/identifier | "doi:10.1006/dbio.2001.0491"xsd:string |
| http://purl.uniprot.org/citations/11784104 | http://purl.org/dc/terms/identifier | "doi:10.1006/dbio.2001.0491"xsd:string |
| http://purl.uniprot.org/citations/11784104 | http://purl.uniprot.org/core/author | "Loomis W.F."xsd:string |
| http://purl.uniprot.org/citations/11784104 | http://purl.uniprot.org/core/author | "Loomis W.F."xsd:string |
| http://purl.uniprot.org/citations/11784104 | http://purl.uniprot.org/core/author | "Fuller D."xsd:string |
| http://purl.uniprot.org/citations/11784104 | http://purl.uniprot.org/core/author | "Fuller D."xsd:string |
| http://purl.uniprot.org/citations/11784104 | http://purl.uniprot.org/core/author | "Chae S.-C."xsd:string |
| http://purl.uniprot.org/citations/11784104 | http://purl.uniprot.org/core/author | "Chae S.-C."xsd:string |
| http://purl.uniprot.org/citations/11784104 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11784104 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11784104 | http://purl.uniprot.org/core/name | "Dev. Biol."xsd:string |
| http://purl.uniprot.org/citations/11784104 | http://purl.uniprot.org/core/name | "Dev. Biol."xsd:string |
| http://purl.uniprot.org/citations/11784104 | http://purl.uniprot.org/core/pages | "183-194"xsd:string |
| http://purl.uniprot.org/citations/11784104 | http://purl.uniprot.org/core/pages | "183-194"xsd:string |
| http://purl.uniprot.org/citations/11784104 | http://purl.uniprot.org/core/title | "Altered cell-type proportioning in Dictyostelium lacking adenosine monophosphate deaminase."xsd:string |
| http://purl.uniprot.org/citations/11784104 | http://purl.uniprot.org/core/title | "Altered cell-type proportioning in Dictyostelium lacking adenosine monophosphate deaminase."xsd:string |
| http://purl.uniprot.org/citations/11784104 | http://purl.uniprot.org/core/volume | "241"xsd:string |
| http://purl.uniprot.org/citations/11784104 | http://purl.uniprot.org/core/volume | "241"xsd:string |
| http://purl.uniprot.org/citations/11784104 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11784104 |
| http://purl.uniprot.org/citations/11784104 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11784104 |
| http://purl.uniprot.org/citations/11784104 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11784104 |
| http://purl.uniprot.org/citations/11784104 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11784104 |