http://purl.uniprot.org/citations/11793416 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11793416 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11793416 | http://www.w3.org/2000/01/rdf-schema#comment | "We have designed novel DNA primers that allow us to detect the expression of the subunits of chorionic gonadotropin (CG) from a variety of species of the order Primates. Using these primers, reverse transcriptase-polymerase chain reaction (RT-PCR), and standard cloning techniques, we detected the expression of a single gene for the common glycoprotein hormone (GPH) alpha-subunit and at least two genes for the CG beta-subunit in trophoblasts of Macaca fascicularis (cynomolgous macaque (cm)) at gestational day (GD) = 26 (+/-2d). No cmCG expression was detected at GD = 35-40. When sequences of cmGPH-alpha and cmCG-beta genes were compared to the corresponding genes of other primates, we found that the alpha-subunit of M. fascicularis was highly conserved compared to other primate species. However, cmCG beta-subunits appeared to be less conserved, residing between those of human CG-beta and baboon CG-beta when analyzed phylogenetically. Of particular interest was a three amino acid stretch in one of the expressed cmCG-beta genes that is distinct from all other primates studied. Our findings imply that not only does the expression of multiple CG beta-subunit genes appear to be common to Old World monkeys, but that the presented methodology will greatly facilitate our ability to understand primate evolution."xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.org/dc/terms/identifier | "doi:10.1002/ajp.1066"xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.org/dc/terms/identifier | "doi:10.1002/ajp.1066"xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/author | "Matsumoto K."xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/author | "Matsumoto K."xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/author | "Bedows E."xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/author | "Bedows E."xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/author | "Lasley B.L."xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/author | "Lasley B.L."xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/author | "Laughlin L.S."xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/author | "Laughlin L.S."xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/author | "Wilken J.A."xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/author | "Wilken J.A."xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/name | "Am. J. Primatol."xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/name | "Am. J. Primatol."xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/pages | "89-97"xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/pages | "89-97"xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/title | "Comparison of chorionic gonadotropin expression in human and macaque (Macaca fascicularis) trophoblasts."xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/title | "Comparison of chorionic gonadotropin expression in human and macaque (Macaca fascicularis) trophoblasts."xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/volume | "56"xsd:string |
http://purl.uniprot.org/citations/11793416 | http://purl.uniprot.org/core/volume | "56"xsd:string |