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| http://purl.uniprot.org/citations/11801597 | http://www.w3.org/2000/01/rdf-schema#comment | "Class IX myosins are unique among the many classes of known actin-based motors in that the tail region of these myosins contains a GTPase-activating protein domain for the small GTP-binding protein, Rho. Previous studies on human myosin-IXb indicate that this myosin is mechanochemically active and exhibits actin-binding properties similar to the processive motor, myosin-Va. Motility analysis of antibody-tethered myosin-IXb performed using the sliding actin filament assay indicates that this myosin does exhibit properties characteristic of a processive motor. Like myosin-Va, the velocity of myosin-IXb remains constant (38.2 +/-1.2 nm/s) even at single motor/filament densities. At low motor densities, filaments can be seen passing through and pivoting about single points on the motility surface. Analysis of filament landing rates as a function of motor density also indicates that a single motor is sufficient for filament movement. However, in contrast to myosin-Va, which uses coordinated motion of its two heads to move processively along the filament, hydrodynamic and chemical cross-linking studies indicate that under the conditions tested, myosin-IXb is a single-headed motor consisting of a single heavy chain and associated light chains."xsd:string |
| http://purl.uniprot.org/citations/11801597 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m111173200"xsd:string |
| http://purl.uniprot.org/citations/11801597 | http://purl.uniprot.org/core/author | "Mooseker M.S."xsd:string |
| http://purl.uniprot.org/citations/11801597 | http://purl.uniprot.org/core/author | "Hayward A."xsd:string |
| http://purl.uniprot.org/citations/11801597 | http://purl.uniprot.org/core/author | "Tyska M.J."xsd:string |
| http://purl.uniprot.org/citations/11801597 | http://purl.uniprot.org/core/author | "O'Connell C.B."xsd:string |
| http://purl.uniprot.org/citations/11801597 | http://purl.uniprot.org/core/author | "Post P.L."xsd:string |
| http://purl.uniprot.org/citations/11801597 | http://purl.uniprot.org/core/author | "Johung K."xsd:string |
| http://purl.uniprot.org/citations/11801597 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11801597 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/11801597 | http://purl.uniprot.org/core/pages | "11679-11683"xsd:string |
| http://purl.uniprot.org/citations/11801597 | http://purl.uniprot.org/core/title | "Myosin-IXb is a single-headed and processive motor."xsd:string |
| http://purl.uniprot.org/citations/11801597 | http://purl.uniprot.org/core/volume | "277"xsd:string |
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