| http://purl.uniprot.org/citations/11802162 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11802162 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11802162 | http://www.w3.org/2000/01/rdf-schema#comment | "Adaptors are heterotetrameric complexes that mediate the incorporation of cargo into transport vesicles by interacting with sorting signals present in the cytosolic domain of transmembrane proteins. Four adaptors, AP-1 (beta 1, gamma, mu 1A or mu 1B, sigma 1), AP-2 (beta 2, alpha, mu 2, sigma 2), AP-3 (beta 3 , delta, mu 3, sigma 3) or AP-4 (beta 4, epsilon, mu 4, sigma 4), have been characterized. AP-1 and AP-3 mediate sorting events at the level of the TGN and/or endosomes, whereas AP-2 functions in endocytic clathrin coated vesicle formation; no function is known so far for AP-4. Here, we show that AP-4 can bind different types of cytosolic signals known to mediate basolateral transport in epithelial cells. Furthermore, in MDCK cells with depleted mu 4 protein levels, several basolateral proteins are mis-sorted to the apical surface, showing that AP-4 participates in basolateral sorting in epithelial cells."xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncb745"xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncb745"xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/author | "Tikkanen R."xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/author | "Tikkanen R."xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/author | "Hoening S."xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/author | "Hoening S."xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/author | "Hunziker W."xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/author | "Hunziker W."xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/author | "Icking A."xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/author | "Icking A."xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/author | "Simmen T."xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/author | "Simmen T."xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/name | "Nat. Cell Biol."xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/name | "Nat. Cell Biol."xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/pages | "154-159"xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/pages | "154-159"xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/title | "AP-4 binds basolateral signals and participates in basolateral sorting in epithelial MDCK cells."xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/title | "AP-4 binds basolateral signals and participates in basolateral sorting in epithelial MDCK cells."xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/volume | "4"xsd:string |
| http://purl.uniprot.org/citations/11802162 | http://purl.uniprot.org/core/volume | "4"xsd:string |