| http://purl.uniprot.org/citations/11811792 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11811792 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11811792 | http://www.w3.org/2000/01/rdf-schema#comment | "We investigated the effect of placenta growth factor-1 (P1GF-1) on cell growth and on the release of nitric oxide (NO), cyclic AMP (cAMP) and cyclic GMP (cGMP) in human malignant epithelial cells. A noteworthy increase in proliferation was induced in choriocarcinoma cells (BeWo) by P1GF-1 treatment, while breast cancer cells (CG-5) were minimally affected. Western blotting and immunocytochemistry demonstrated the expression of the P1GF-1 receptor fms-like tyrosine kinase-1 (Flt-1) in these models. NO was released in the BeWo culture medium as a result of P1GF-1 treatment, with maximal induction occurring after 6 h. Enhanced cAMP levels were observed after 80 min-6 h, while the amounts of cGMP produced were undetectable. In summary, PIGF-1 stimulates the proliferation of cell types that express Flt-1, other than endothelial cells. In BeWo cells, this effect is preceded by the induction of NO and cAMP as probable downstream effectors of Flt-1 activation."xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.org/dc/terms/identifier | "doi:10.3109/08977190109001086"xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.org/dc/terms/identifier | "doi:10.3109/08977190109001086"xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/author | "Maglione D."xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/author | "Maglione D."xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/author | "Angelucci C."xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/author | "Angelucci C."xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/author | "Sica G."xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/author | "Sica G."xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/author | "Lama G."xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/author | "Lama G."xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/author | "Iacopino F."xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/author | "Iacopino F."xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/name | "Growth Factors"xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/name | "Growth Factors"xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/pages | "193-206"xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/pages | "193-206"xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/title | "Effect of placenta growth factor-1 on proliferation and release of nitric oxide, cyclic AMP and cyclic GMP in human epithelial cells expressing the FLT-1 receptor."xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/title | "Effect of placenta growth factor-1 on proliferation and release of nitric oxide, cyclic AMP and cyclic GMP in human epithelial cells expressing the FLT-1 receptor."xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/volume | "19"xsd:string |
| http://purl.uniprot.org/citations/11811792 | http://purl.uniprot.org/core/volume | "19"xsd:string |