http://purl.uniprot.org/citations/11812785 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11812785 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11812785 | http://www.w3.org/2000/01/rdf-schema#comment | "DOC-2/DAB2 is a member of the disable gene family with tumor-inhibitory activity. Its down-regulation is associated with several neoplasms, and serine phosphorylation of its N terminus modulates DOC-2/DAB2's inhibitory effect on AP-1 transcriptional activity. We describe the cloning of DIP1/2, a novel gene that interacts with the N-terminal domain of DOC-2/DAB2. DIP1/2 is a novel GTPase-activating protein containing a Ras GTPase-activating protein homology domain (N terminus) and two other unique domains (i.e. 10 proline repeats and leucine zipper). Interaction between DOC-2/DAB2 and DIP1/2 is detected in normal tissues such as the brain and prostate. Altered expression of these two proteins is often detected in prostate cancer cells. Indeed, the presence of DIP1/2 effectively blocks mitogen-induced gene expression and inhibits the growth of prostate cancer. Thus, DOC-2/DAB2 and DIP1/2 appear to represent a unique negative regulatory complex that maintains cell homeostasis."xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m110568200"xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m110568200"xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/author | "Chen H."xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/author | "Chen H."xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/author | "Wang Z."xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/author | "Wang Z."xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/author | "McConnell J.D."xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/author | "McConnell J.D."xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/author | "Tseng C.-P."xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/author | "Tseng C.-P."xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/author | "Hsieh J.-T."xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/author | "Hsieh J.-T."xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/author | "Navone N."xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/author | "Navone N."xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/author | "Pong R.-C."xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/author | "Pong R.-C."xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/pages | "12622-12631"xsd:string |
http://purl.uniprot.org/citations/11812785 | http://purl.uniprot.org/core/pages | "12622-12631"xsd:string |