http://purl.uniprot.org/citations/11834724 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11834724 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11834724 | http://www.w3.org/2000/01/rdf-schema#comment | "The Xrcc2 and Rad51D/Rad51L3 proteins, which belong to the Rad51 paralogs, are required for homologous recombinational repair (HRR) in vertebrates. The Xrcc2 and Rad51D/Rad51L3 genes, whose products interact with each other, have essential roles in ensuring normal embryonic development. In the present study, we coexpressed the human Xrcc2 and Rad51D/Rad51L3 proteins (Xrcc2 and Rad51D, respectively) in Escherichia coli, and purified the Xrcc2*Rad51D complex to homogeneity. The Xrcc2 small middle dotRad51D complex catalyzed homologous pairing between single-stranded and double-stranded DNA, similar to the function of the Xrcc3*Rad51C complex, which is another complex of the Rad51 paralogs. An electron microscopic analysis showed that Xrcc2*Rad51D formed a multimeric ring structure in the absence of DNA. In the presence of ssDNA, Xrcc2*Rad51D formed a filamentous structure, which is commonly observed among the human homologous pairing proteins, Rad51, Rad52, and Xrcc3*Rad51C."xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m105719200"xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m105719200"xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/author | "Ikawa S."xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/author | "Ikawa S."xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/author | "Shibata T."xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/author | "Shibata T."xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/author | "Yokoyama S."xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/author | "Yokoyama S."xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/author | "Kagawa W."xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/author | "Kagawa W."xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/author | "Kurumizaka H."xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/author | "Kurumizaka H."xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/author | "Nakada M."xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/author | "Nakada M."xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/author | "Yamazoe M."xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/author | "Yamazoe M."xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/author | "Enomoto R."xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/author | "Enomoto R."xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/author | "Kinebuchi T."xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/author | "Kinebuchi T."xsd:string |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/11834724 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |