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http://purl.uniprot.org/citations/11847343http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11847343http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11847343http://www.w3.org/2000/01/rdf-schema#comment"GSK3/SHAGGY is a highly conserved serine/threonine kinase implicated in many signaling pathways in eukaryotes. Although many GSK3/SHAGGY-like kinases have been identified in plants, little is known about their functions in plant growth and development. Here we show that the Arabidopsis BRASSINOSTEROID-INSENSITIVE 2 (BIN2) gene encodes a GSK3/SHAGGY-like kinase. Gain-of-function mutations within its coding sequence or its overexpression inhibit brassinosteroid (BR) signaling, resulting in plants that resemble BR-deficient and BR-response mutants. In contrast, reduced BIN2 expression via cosuppression partially rescues a weak BR-signaling mutation. Thus, BIN2 acts as a negative regulator to control steroid signaling in plants."xsd:string
http://purl.uniprot.org/citations/11847343http://purl.org/dc/terms/identifier"doi:10.1126/science.1065769"xsd:string
http://purl.uniprot.org/citations/11847343http://purl.org/dc/terms/identifier"doi:10.1126/science.1065769"xsd:string
http://purl.uniprot.org/citations/11847343http://purl.uniprot.org/core/author"Li J."xsd:string
http://purl.uniprot.org/citations/11847343http://purl.uniprot.org/core/author"Li J."xsd:string
http://purl.uniprot.org/citations/11847343http://purl.uniprot.org/core/author"Nam K.H."xsd:string
http://purl.uniprot.org/citations/11847343http://purl.uniprot.org/core/author"Nam K.H."xsd:string
http://purl.uniprot.org/citations/11847343http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/11847343http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/11847343http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/11847343http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/11847343http://purl.uniprot.org/core/pages"1299-1301"xsd:string
http://purl.uniprot.org/citations/11847343http://purl.uniprot.org/core/pages"1299-1301"xsd:string
http://purl.uniprot.org/citations/11847343http://purl.uniprot.org/core/title"Regulation of brassinosteroid signaling by a GSK3/SHAGGY-like kinase."xsd:string
http://purl.uniprot.org/citations/11847343http://purl.uniprot.org/core/title"Regulation of brassinosteroid signaling by a GSK3/SHAGGY-like kinase."xsd:string
http://purl.uniprot.org/citations/11847343http://purl.uniprot.org/core/volume"295"xsd:string
http://purl.uniprot.org/citations/11847343http://purl.uniprot.org/core/volume"295"xsd:string
http://purl.uniprot.org/citations/11847343http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11847343
http://purl.uniprot.org/citations/11847343http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11847343
http://purl.uniprot.org/citations/11847343http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11847343
http://purl.uniprot.org/citations/11847343http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11847343
http://purl.uniprot.org/uniprot/Q39011http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/11847343
http://purl.uniprot.org/uniprot/Q39011#attribution-73EC35F31E6E1525E7F2C2948ABB5591http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/11847343