| http://purl.uniprot.org/citations/11850834 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11850834 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11850834 | http://www.w3.org/2000/01/rdf-schema#comment | "The expression of a gene, designated as Retroviral insertion site (Ris)2, was activated by retroviral DNA integration in an immortalized primitive erythroid cell line, EB-PE. Ris2 was also expressed at high levels in all human tumor cell lines analysed. Consistently, NIH3T3 fibroblasts overexpressing Ris2 formed tumors in Rag2 -/-mice when injected subcutaneously. The putative RIS2 protein shows a high sequence similarity to Xenopus CDT1, Drosophila DUP, and human CDT1, a newly identified DNA replication licensing protein, suggesting that Ris2 is a mouse homologue of CDT1. Cells overexpressing Ris2/Cdt1 exhibited a quicker entry into S phase when released from serum starvation compared to controls. Our results suggest that CDT1, an essential licensing protein for DNA replication, can function as an oncogene in mammals."xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.onc.1205175"xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.onc.1205175"xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/author | "Fremont D.H."xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/author | "Fremont D.H."xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/author | "Seo J."xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/author | "Seo J."xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/author | "Choi K."xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/author | "Choi K."xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/author | "Moon E."xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/author | "Moon E."xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/author | "Arentson E."xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/author | "Arentson E."xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/author | "Faloon P."xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/author | "Faloon P."xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/author | "Studts J.M."xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/author | "Studts J.M."xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/pages | "1150-1158"xsd:string |
| http://purl.uniprot.org/citations/11850834 | http://purl.uniprot.org/core/pages | "1150-1158"xsd:string |