http://purl.uniprot.org/citations/11859154 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11859154 | http://www.w3.org/2000/01/rdf-schema#comment | "Group II self-splicing introns catalyze autoexcision from precursor RNA transcripts by a mechanism strikingly similar to that of the spliceosome, an RNA-protein assembly responsible for splicing together the protein-coding parts of most eukaryotic pre-mRNAs. Splicing in both cases initiates via nucleophilic attack at the 5' splice site by the 2' OH of a conserved intron adenosine residue, creating a branched (lariat) intermediate. Here, we describe the crystal structure at 3.0 A resolution of a 70-nucleotide RNA containing the catalytically essential domains 5 and 6 of the yeast ai5gamma group II self-splicing intron, revealing an unexpected two-nucleotide bulged structure around the branch-point adenosine in domain 6."xsd:string |
http://purl.uniprot.org/citations/11859154 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1069268"xsd:string |
http://purl.uniprot.org/citations/11859154 | http://purl.uniprot.org/core/author | "Doudna J.A."xsd:string |
http://purl.uniprot.org/citations/11859154 | http://purl.uniprot.org/core/author | "Zhang L."xsd:string |
http://purl.uniprot.org/citations/11859154 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/11859154 | http://purl.uniprot.org/core/name | "Science"xsd:string |
http://purl.uniprot.org/citations/11859154 | http://purl.uniprot.org/core/pages | "2084-2088"xsd:string |
http://purl.uniprot.org/citations/11859154 | http://purl.uniprot.org/core/title | "Structural insights into group II intron catalysis and branch-site selection."xsd:string |
http://purl.uniprot.org/citations/11859154 | http://purl.uniprot.org/core/volume | "295"xsd:string |
http://purl.uniprot.org/citations/11859154 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11859154 |
http://purl.uniprot.org/citations/11859154 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11859154 |
http://purl.uniprot.org/uniprot/#_P00401-mappedCitation-11859154 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11859154 |
http://purl.uniprot.org/uniprot/P00401 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/11859154 |