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http://purl.uniprot.org/citations/11859196http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11859196http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11859196http://www.w3.org/2000/01/rdf-schema#comment"The identification of pathways mediated by the kinase Cdk5 and the ligand reelin has provided a conceptual framework for exploring the molecular mechanisms underlying proper lamination of the developing mammalian cerebral cortex. In this report, we identify a component of the regulation of Cdk5-mediated cortical lamination by genetic analysis of the roles of the class III POU domain transcription factors, Brn-1 and Brn-2, expressed during the development of the forebrain and coexpressed in most layer II-V cortical neurons. Brn-1 and Brn-2 appear to critically control the initiation of radial migration, redundantly regulating the cell-autonomous expression of the p35 and p39 regulatory subunits of Cdk5 in migrating cortical neurons, with Brn-1(-/-)/Brn-2(-/-) mice exhibiting cortical inversion."xsd:string
http://purl.uniprot.org/citations/11859196http://purl.org/dc/terms/identifier"doi:10.1126/science.1067132"xsd:string
http://purl.uniprot.org/citations/11859196http://purl.org/dc/terms/identifier"doi:10.1126/science.1067132"xsd:string
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/author"McEvilly R.J."xsd:string
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/author"McEvilly R.J."xsd:string
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/author"Rosenfeld M.G."xsd:string
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/author"Rosenfeld M.G."xsd:string
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/author"Schonemann M.D."xsd:string
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/author"Schonemann M.D."xsd:string
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/author"Hooshmand F."xsd:string
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/author"Hooshmand F."xsd:string
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/author"de Diaz M.O."xsd:string
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/author"de Diaz M.O."xsd:string
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/pages"1528-1532"xsd:string
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/pages"1528-1532"xsd:string
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/title"Transcriptional regulation of cortical neuron migration by POU domain factors."xsd:string
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/title"Transcriptional regulation of cortical neuron migration by POU domain factors."xsd:string
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/volume"295"xsd:string
http://purl.uniprot.org/citations/11859196http://purl.uniprot.org/core/volume"295"xsd:string