| http://purl.uniprot.org/citations/11861479 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11861479 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11861479 | http://www.w3.org/2000/01/rdf-schema#comment | "The cortical regions of the brain are laminated as a result of directed migration of precursor cells along glia during development. Previously, we have used an assay system to identify astrotactin as a neuronal ligand for migration on glial fibers. To examine the function of astrotactin in vivo, we generated a null mutation by targeted gene disruption. The cerebella of astrotactin null mice are approximately 10% smaller than wild type. In vitro and in vivo cerebellar granule cell assays show a decrease in neuron-glial binding, a reduction in migration rates and abnormal development of Purkinje cells. Consequences of this are poorer balance and coordination. Thus, astrotactin functions in migration along glial processes in vivo, a process required for generating laminar structures and for the development of synaptic partner systems."xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.org/dc/terms/identifier | "doi:10.1242/dev.129.4.965"xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.org/dc/terms/identifier | "doi:10.1242/dev.129.4.965"xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/author | "Cooper M."xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/author | "Cooper M."xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/author | "Adams N.C."xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/author | "Adams N.C."xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/author | "Dietz G."xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/author | "Dietz G."xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/author | "Hatten M.E."xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/author | "Hatten M.E."xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/author | "Tomoda T."xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/author | "Tomoda T."xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/name | "Development"xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/name | "Development"xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/pages | "965-972"xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/pages | "965-972"xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/title | "Mice that lack astrotactin have slowed neuronal migration."xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/title | "Mice that lack astrotactin have slowed neuronal migration."xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/volume | "129"xsd:string |
| http://purl.uniprot.org/citations/11861479 | http://purl.uniprot.org/core/volume | "129"xsd:string |