| http://purl.uniprot.org/citations/11867533 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11867533 | http://www.w3.org/2000/01/rdf-schema#comment | "Insulin-like growth factor II receptor (IGF2R) is a multifunctional cell surface receptor implicated in tumour suppression. Its growth inhibitory activity has been associated with an ability to bind IGF-II. IGF2R contains 15 homologous extracellular domains, with domain 11 primarily responsible for IGF-II binding. We report a 1.4 A resolution crystal structure of domain 11, solved using the anomalous scattering signal of sulfur. The structure consists of two crossed beta-sheets forming a flattened beta-barrel. Structural analysis identifies the putative IGF-II binding site at one end of the beta-barrel whilst crystal lattice contacts suggest a model for the full-length IGF2R extracellular region. The structure factors and coordinates of IGF2R domain 11 have been deposited in the Protein Data Bank (accession codes 1GP0 and 1GP3)."xsd:string |
| http://purl.uniprot.org/citations/11867533 | http://purl.org/dc/terms/identifier | "doi:10.1093/emboj/21.5.1054"xsd:string |
| http://purl.uniprot.org/citations/11867533 | http://purl.uniprot.org/core/author | "Jones M.A."xsd:string |
| http://purl.uniprot.org/citations/11867533 | http://purl.uniprot.org/core/author | "Brown J."xsd:string |
| http://purl.uniprot.org/citations/11867533 | http://purl.uniprot.org/core/author | "Harlos K."xsd:string |
| http://purl.uniprot.org/citations/11867533 | http://purl.uniprot.org/core/author | "Jones E.Y."xsd:string |
| http://purl.uniprot.org/citations/11867533 | http://purl.uniprot.org/core/author | "Esnouf R.M."xsd:string |
| http://purl.uniprot.org/citations/11867533 | http://purl.uniprot.org/core/author | "Hassan A.B."xsd:string |
| http://purl.uniprot.org/citations/11867533 | http://purl.uniprot.org/core/author | "Linnell J."xsd:string |
| http://purl.uniprot.org/citations/11867533 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11867533 | http://purl.uniprot.org/core/name | "EMBO J"xsd:string |
| http://purl.uniprot.org/citations/11867533 | http://purl.uniprot.org/core/pages | "1054-1062"xsd:string |
| http://purl.uniprot.org/citations/11867533 | http://purl.uniprot.org/core/title | "Structure of a functional IGF2R fragment determined from the anomalous scattering of sulfur."xsd:string |
| http://purl.uniprot.org/citations/11867533 | http://purl.uniprot.org/core/volume | "21"xsd:string |
| http://purl.uniprot.org/citations/11867533 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11867533 |
| http://purl.uniprot.org/citations/11867533 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11867533 |
| http://purl.uniprot.org/uniprot/#_A0N9R6-mappedCitation-11867533 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11867533 |
| http://purl.uniprot.org/uniprot/#_A0N9R7-mappedCitation-11867533 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11867533 |
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| http://purl.uniprot.org/uniprot/#_Q13661-mappedCitation-11867533 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11867533 |
| http://purl.uniprot.org/uniprot/#_Q59EZ3-mappedCitation-11867533 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11867533 |
| http://purl.uniprot.org/uniprot/#_P11717-mappedCitation-11867533 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11867533 |