| http://purl.uniprot.org/citations/11876640 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11876640 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11876640 | http://www.w3.org/2000/01/rdf-schema#comment | "Arrestin binding to activated, phosphorylated G protein-coupled receptors (GPCRs) represents a critical step in regulation of light- and hormone-dependent signaling. Nonvisual arrestins, such as arrestin-2, interact with multiple proteins for the purpose of propagating and terminating signaling events. Using a combination of X-ray crystallography, molecular modeling, mutagenesis, and binding analysis, we reveal structural features of arrestin-2 that may enable simultaneous binding to phosphorylated receptor, SH3 domains, phosphoinositides, and beta-adaptin. The structure of full-length arrestin-2 thus provides a uniquely oriented scaffold for assembly of multiple, diverse molecules involved in GPCR signal transduction."xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.org/dc/terms/identifier | "doi:10.1021/bi015905j"xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.org/dc/terms/identifier | "doi:10.1021/bi015905j"xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/author | "Benovic J.L."xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/author | "Benovic J.L."xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/author | "Brenner C."xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/author | "Brenner C."xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/author | "Kim Y.-M."xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/author | "Kim Y.-M."xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/author | "Milano S.K."xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/author | "Milano S.K."xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/author | "Pace H.C."xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/author | "Pace H.C."xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/name | "Biochemistry"xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/name | "Biochemistry"xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/pages | "3321-3328"xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/pages | "3321-3328"xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/title | "Scaffolding functions of arrestin-2 revealed by crystal structure and mutagenesis."xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/title | "Scaffolding functions of arrestin-2 revealed by crystal structure and mutagenesis."xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/volume | "41"xsd:string |
| http://purl.uniprot.org/citations/11876640 | http://purl.uniprot.org/core/volume | "41"xsd:string |