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| http://purl.uniprot.org/citations/11884510 | http://www.w3.org/2000/01/rdf-schema#comment | "The PX domain, which until recently was an orphan domain, has emerged as the latest member of the phosphoinositide-binding module superfamily. Structural studies have revealed that it has a novel fold and identified key residues that interact with the bound phosphoinositide, enabling some prediction of phosphoinositide-binding specificity. Specificity for PtdIns(3)P appears to be the most common, and several proteins containing PX domains localise to PtdIns(3)P-rich endosomal and vacuolar structures through their PX domains: these include the yeast t-SNARE Vam7p, mammalian sorting nexins (involved in membrane trafficking events) and the Ser/Thr kinase CISK, which is implicated in cell survival. Additionally, phosphoinositide binding to the PX domains of p40(phox) and p47(phox) appears to play a critical role in the active assembly of the neutrophil oxidase complex."xsd:string |
| http://purl.uniprot.org/citations/11884510 | http://purl.org/dc/terms/identifier | "doi:10.1242/jcs.115.6.1099"xsd:string |
| http://purl.uniprot.org/citations/11884510 | http://purl.uniprot.org/core/author | "Andrews S."xsd:string |
| http://purl.uniprot.org/citations/11884510 | http://purl.uniprot.org/core/author | "Hawkins P.T."xsd:string |
| http://purl.uniprot.org/citations/11884510 | http://purl.uniprot.org/core/author | "Stephens L.R."xsd:string |
| http://purl.uniprot.org/citations/11884510 | http://purl.uniprot.org/core/author | "Ellson C.D."xsd:string |
| http://purl.uniprot.org/citations/11884510 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11884510 | http://purl.uniprot.org/core/name | "J Cell Sci"xsd:string |
| http://purl.uniprot.org/citations/11884510 | http://purl.uniprot.org/core/pages | "1099-1105"xsd:string |
| http://purl.uniprot.org/citations/11884510 | http://purl.uniprot.org/core/title | "The PX domain: a new phosphoinositide-binding module."xsd:string |
| http://purl.uniprot.org/citations/11884510 | http://purl.uniprot.org/core/volume | "115"xsd:string |
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