| http://purl.uniprot.org/citations/11891216 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11891216 | http://www.w3.org/2000/01/rdf-schema#comment | "Using sequence homology searches, yeast two-hybrid assays and glutathione S-transferase (GST)-pull-down approaches we have identified a series of glutamate receptor subunits that interact differentially with the PDZ proteins GRIP, PICK1, and syntenin. GST-pull-down experiments identified more interactions than detected by yeast two-hybrid assays. We report several receptor-protein interactions, strong ones include: (i) GRIP and syntenin with mGluR7a, mGluR4a, and mGluR6; (ii) PICK1 and GRIP with mGluR3; and (iii) syntenin with all forms of GluR1-4 and mGluR7b. We further characterized the novel mGluR7a-GRIP interaction found both in yeast two-hybrid and GST-pull-down assays and observed that mGluR7a localization overlapped with GRIP with in hippocampal neurons. The wide range of targets for PICK1, GRIP, and syntenin suggests they may represent a molecular mechanism that can concentrate and/or regulate a number of different receptors at a common site on a synapse. These data also suggest that the structural determinants involved in PDZ interactions are more complex than originally envisaged."xsd:string |
| http://purl.uniprot.org/citations/11891216 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.c200112200"xsd:string |
| http://purl.uniprot.org/citations/11891216 | http://purl.uniprot.org/core/author | "Nakanishi S."xsd:string |
| http://purl.uniprot.org/citations/11891216 | http://purl.uniprot.org/core/author | "Meyer G."xsd:string |
| http://purl.uniprot.org/citations/11891216 | http://purl.uniprot.org/core/author | "Henley J.M."xsd:string |
| http://purl.uniprot.org/citations/11891216 | http://purl.uniprot.org/core/author | "Dev K.K."xsd:string |
| http://purl.uniprot.org/citations/11891216 | http://purl.uniprot.org/core/author | "Nishimune A."xsd:string |
| http://purl.uniprot.org/citations/11891216 | http://purl.uniprot.org/core/author | "Hirbec H."xsd:string |
| http://purl.uniprot.org/citations/11891216 | http://purl.uniprot.org/core/author | "Perestenko O."xsd:string |
| http://purl.uniprot.org/citations/11891216 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11891216 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/11891216 | http://purl.uniprot.org/core/pages | "15221-15224"xsd:string |
| http://purl.uniprot.org/citations/11891216 | http://purl.uniprot.org/core/title | "The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs."xsd:string |
| http://purl.uniprot.org/citations/11891216 | http://purl.uniprot.org/core/volume | "277"xsd:string |
| http://purl.uniprot.org/citations/11891216 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11891216 |
| http://purl.uniprot.org/citations/11891216 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11891216 |
| http://purl.uniprot.org/uniprot/#_A0A0G2K6Y0-mappedCitation-11891216 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11891216 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JU28-mappedCitation-11891216 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11891216 |
| http://purl.uniprot.org/uniprot/#_A0A8I5ZUN6-mappedCitation-11891216 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11891216 |
| http://purl.uniprot.org/uniprot/#_A0A140TA96-mappedCitation-11891216 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11891216 |
| http://purl.uniprot.org/uniprot/#_A0A8I6AK56-mappedCitation-11891216 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11891216 |
| http://purl.uniprot.org/uniprot/#_A0A8I6AKP3-mappedCitation-11891216 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11891216 |
| http://purl.uniprot.org/uniprot/#_A0A8I6GB39-mappedCitation-11891216 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11891216 |
| http://purl.uniprot.org/uniprot/#_A0A8I6GEA5-mappedCitation-11891216 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11891216 |