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http://purl.uniprot.org/citations/11892998http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11892998http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11892998http://www.w3.org/2000/01/rdf-schema#comment"Beta-mannosidase is an exoglycosidase involved in the degradation of N-linked oligosaccharides moieties of glycoproteins. Lack of beta-mannosidase activity leads to the lysosomal disorder beta-mannosidosis (MIM 248510). We have isolated and sequenced the gene encoding the mouse beta-mannosidase. Comparison of the deduced amino acid sequence of mouse, human, bovine, and goat beta-mannosidase showed 64%, identity, reflecting a high degree of evolutionary conservation. Analysis of a multiple tissue northern blotting revealed a major transcript of about 3.7 kb in all tissues examined. The northern analysis also demonstrates that there is differential tissue mRNA expression. The mouse beta-mannosidase gene (Bmn) was mapped to the distal end of Chromosome (Chr) 3, in a region that is homologous with a segment of human Chr 4 containing the orthologous human gene."xsd:string
http://purl.uniprot.org/citations/11892998http://purl.org/dc/terms/identifier"doi:10.1023/a:1013286216030"xsd:string
http://purl.uniprot.org/citations/11892998http://purl.org/dc/terms/identifier"doi:10.1023/a:1013286216030"xsd:string
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/author"Orlacchio A."xsd:string
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/author"Orlacchio A."xsd:string
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/author"Beccari T."xsd:string
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/author"Beccari T."xsd:string
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/author"Stirling J.L."xsd:string
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/author"Stirling J.L."xsd:string
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/author"Bibi L."xsd:string
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/author"Bibi L."xsd:string
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/author"Stinchi S."xsd:string
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/author"Stinchi S."xsd:string
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/name"Biosci. Rep."xsd:string
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/name"Biosci. Rep."xsd:string
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/pages"315-323"xsd:string
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/pages"315-323"xsd:string
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/title"Mouse beta-mannosidase, cDNA cloning, expression, and chromosomal localization."xsd:string
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/title"Mouse beta-mannosidase, cDNA cloning, expression, and chromosomal localization."xsd:string
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/volume"21"xsd:string
http://purl.uniprot.org/citations/11892998http://purl.uniprot.org/core/volume"21"xsd:string