| http://purl.uniprot.org/citations/11907248 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11907248 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11907248 | http://www.w3.org/2000/01/rdf-schema#comment | "We examined 41 human and animal rotavirus strains representative of all known P genotypes for their dependency on cellular N-acetylneuraminic (sialic) acid (SA) residues for infectivity. Our results showed that all rotaviruses studied, whether of animal or human origin, belonging to P genotypes [1], [2], [3], and [7] depended on SA residues on the cell surface for efficient infectivity but that all human and animal rotavirus strains representative of the remaining known P genotypes were SA independent. The SA residue requirement for efficient infectivity did not change for reassortant rotavirus strains with altered VP4-VP7 combinations. The initial interaction of rotavirus strains with SA residues on the cell surface correlated with VP4 genotype specificity, not with species of origin or VP7 G serotype specificity (P = 0.001; r2 = 1.00, Pearson's correlation coefficient). In addition to being a requirement for infectivity, the presence of SA residues on the cell surface is a requirement for efficient growth in cell culture; recognition of the association of specific P genotypes with the binding of rotavirus to SA residues will facilitate our understanding of the molecular basis of the early events of rotavirus-cell interactions in cell culture models and of pathogenicity in vivo."xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.org/dc/terms/identifier | "doi:10.1128/jvi.76.8.4087-4095.2002"xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.org/dc/terms/identifier | "doi:10.1128/jvi.76.8.4087-4095.2002"xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/author | "Estes M.K."xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/author | "Estes M.K."xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/author | "Desselberger U."xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/author | "Desselberger U."xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/author | "Ciarlet M."xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/author | "Ciarlet M."xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/author | "Iturriza-Gomara M."xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/author | "Iturriza-Gomara M."xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/author | "Liprandi F."xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/author | "Liprandi F."xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/author | "Ludert J.E."xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/author | "Ludert J.E."xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/author | "Gray J.J."xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/author | "Gray J.J."xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/name | "J. Virol."xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/name | "J. Virol."xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/pages | "4087-4095"xsd:string |
| http://purl.uniprot.org/citations/11907248 | http://purl.uniprot.org/core/pages | "4087-4095"xsd:string |