| http://purl.uniprot.org/citations/11911820 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11911820 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11911820 | http://www.w3.org/2000/01/rdf-schema#comment | "The elongated complementary-determining region (CDR) 3beta found in the unliganded KB5-C20 TCR protrudes from the antigen binding site and prevents its docking onto the peptide/MHC (pMHC) surface according to a canonical diagonal orientation. We now present the crystal structure of a complex involving the KB5-C20 TCR and an octapeptide bound to the allogeneic H-2K(b) MHC class I molecule. This structure reveals how a tremendously large CDR3beta conformational change allows the KB5-C20 TCR to adapt to the rather constrained pMHC surface and achieve a diagonal docking mode. This extreme case of induced fit also shows that TCR plasticity is primarily restricted to CDR3 loops and does not propagate away from the antigen binding site."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1074-7613(02)00288-1"xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1074-7613(02)00288-1"xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Fontecilla-Camps J.C."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Fontecilla-Camps J.C."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Darnault C."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Darnault C."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Housset D."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Housset D."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Gregoire C."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Gregoire C."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Malissen B."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Malissen B."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Mazza G."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Mazza G."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Reiser J.B."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Reiser J.B."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Guimezanes A."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Guimezanes A."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Mosser T."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Mosser T."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Schmitt-Verhulst A.M."xsd:string |
| http://purl.uniprot.org/citations/11911820 | http://purl.uniprot.org/core/author | "Schmitt-Verhulst A.M."xsd:string |