| http://purl.uniprot.org/citations/11922394 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11922394 | http://www.w3.org/2000/01/rdf-schema#comment | "A cDNA microarray analysis indicated that Semaphorin3B (Sema3B), a gene whose product is involved in axon guidance and axonal repulsion, is inducible by p53. Introduction of exogenous p53 into a glioblastoma cell line lacking wild-type p53 (U373MG) dramatically induced expression of Sema3B mRNA. An electrophoretic mobility shift assay and a reporter assay confirmed that a potential p53 binding site present in the promoter region had p53-dependent transcriptional activity. Expression of endogenous Sema3B was induced in response to genotoxic stresses caused by adriamycin treatment or UV irradiation in a p53-dependent manner. Ectopic expression of Sema3B in p53-defective cells reduced the number of colonies in colony formation assays. These results suggest that Sema3B might play some role in regulating cell growth as a mediator of p53 tumor-suppressor activity."xsd:string |
| http://purl.uniprot.org/citations/11922394 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.neo.7900211"xsd:string |
| http://purl.uniprot.org/citations/11922394 | http://purl.uniprot.org/core/author | "Arakawa H."xsd:string |
| http://purl.uniprot.org/citations/11922394 | http://purl.uniprot.org/core/author | "Mori T."xsd:string |
| http://purl.uniprot.org/citations/11922394 | http://purl.uniprot.org/core/author | "Nakamura Y."xsd:string |
| http://purl.uniprot.org/citations/11922394 | http://purl.uniprot.org/core/author | "Toyama Y."xsd:string |
| http://purl.uniprot.org/citations/11922394 | http://purl.uniprot.org/core/author | "Ochi K."xsd:string |
| http://purl.uniprot.org/citations/11922394 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11922394 | http://purl.uniprot.org/core/name | "Neoplasia"xsd:string |
| http://purl.uniprot.org/citations/11922394 | http://purl.uniprot.org/core/pages | "82-87"xsd:string |
| http://purl.uniprot.org/citations/11922394 | http://purl.uniprot.org/core/title | "Identification of semaphorin3B as a direct target of p53."xsd:string |
| http://purl.uniprot.org/citations/11922394 | http://purl.uniprot.org/core/volume | "4"xsd:string |
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