| http://purl.uniprot.org/citations/11923193 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11923193 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11923193 | http://www.w3.org/2000/01/rdf-schema#comment | "A distinct feature of development in the simple eukaryote Dictyostelium discoideum is an aggregative transition from a unicellular to a multicellular phase. Using genome-wide transcriptional analysis we show that this transition is accompanied by a dramatic change in the expression of more than 25% of the genes in the genome. We also show that the transcription patterns of these genes are not sensitive to the strain or the nutritional history, indicating that Dictyostelium development is a robust physiological process that is accompanied by stereotypical transcriptional events. Analysis of the two differentiated cell types, spores and stalk cells, and their precursors revealed a large number of differentially expressed genes as well as unexpected patterns of gene expression, which shed new light on the timing and possible mechanisms of cell-type divergence. Our findings provide new perspectives on the complexity of the developmental program and the fraction of the genome that is regulated during development."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.org/dc/terms/identifier | "doi:10.1242/dev.129.7.1543"xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.org/dc/terms/identifier | "doi:10.1242/dev.129.7.1543"xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Katoh M."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Katoh M."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Ochiai H."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Ochiai H."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Kuwayama H."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Kuwayama H."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Tanaka Y."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Tanaka Y."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Saito T."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Saito T."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Ibarra M."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Ibarra M."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Kuspa A."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Kuspa A."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Maeda M."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Maeda M."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Morio T."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Morio T."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Shaulsky G."xsd:string |
| http://purl.uniprot.org/citations/11923193 | http://purl.uniprot.org/core/author | "Shaulsky G."xsd:string |