http://purl.uniprot.org/citations/11927565 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11927565 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11927565 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Citation |
http://purl.uniprot.org/citations/11927565 | http://www.w3.org/2000/01/rdf-schema#comment | "The genome of Saccharomyces cerevisiae encodes three close homologues of the Escherichia coli 2'-O-rRNA methyltransferase FtsJ/RrmJ, designated Trm7p, Spb1p and Mrm2p. We present evidence that Trm7p methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop, both in vivo and in vitro. In a trm7Delta strain, which is viable but grows slowly, translation is impaired, thus indicating that these tRNA modifications could be important for translation efficiency. We discuss the emergence of a family of three 2'-O-RNA methyltransferases in Eukaryota and one in Prokaryota from a common ancestor. We propose that each eukaryotic enzyme is located in a different cell compartment, in which it would methylate a different RNA that can adopt a very similar secondary structure."xsd:string |
http://purl.uniprot.org/citations/11927565 | http://purl.org/dc/terms/identifier | "doi:10.1093/emboj/21.7.1811"xsd:string |
http://purl.uniprot.org/citations/11927565 | http://purl.org/dc/terms/identifier | "doi:10.1093/emboj/21.7.1811"xsd:string |
http://purl.uniprot.org/citations/11927565 | http://purl.uniprot.org/core/author | "Bujnicki J.M."xsd:string |
http://purl.uniprot.org/citations/11927565 | http://purl.uniprot.org/core/author | "Bujnicki J.M."xsd:string |
http://purl.uniprot.org/citations/11927565 | http://purl.uniprot.org/core/author | "Grosjean H."xsd:string |
http://purl.uniprot.org/citations/11927565 | http://purl.uniprot.org/core/author | "Grosjean H."xsd:string |
http://purl.uniprot.org/citations/11927565 | http://purl.uniprot.org/core/author | "Lecointe F."xsd:string |
http://purl.uniprot.org/citations/11927565 | http://purl.uniprot.org/core/author | "Lecointe F."xsd:string |
http://purl.uniprot.org/citations/11927565 | http://purl.uniprot.org/core/author | "Pintard L."xsd:string |
http://purl.uniprot.org/citations/11927565 | http://purl.uniprot.org/core/author | "Pintard L."xsd:string |
http://purl.uniprot.org/citations/11927565 | http://purl.uniprot.org/core/author | "Lapeyre B."xsd:string |
http://purl.uniprot.org/citations/11927565 | http://purl.uniprot.org/core/author | "Lapeyre B."xsd:string |
http://purl.uniprot.org/citations/11927565 | http://purl.uniprot.org/core/author | "Bonnerot C."xsd:string |
http://purl.uniprot.org/citations/11927565 | http://purl.uniprot.org/core/author | "Bonnerot C."xsd:string |
http://purl.uniprot.org/citations/11927565 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/11927565 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/11927565 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
http://purl.uniprot.org/citations/11927565 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
http://purl.uniprot.org/citations/11927565 | http://purl.uniprot.org/core/pages | "1811-1820"xsd:string |
http://purl.uniprot.org/citations/11927565 | http://purl.uniprot.org/core/pages | "1811-1820"xsd:string |
http://purl.uniprot.org/citations/11927565 | http://purl.uniprot.org/core/title | "Trm7p catalyses the formation of two 2'-O-methylriboses in yeast tRNA anticodon loop."xsd:string |