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http://purl.uniprot.org/citations/11961379http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
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Background

The association between thrombophilic variants (Leiden mutation of the factor V gene, G20210A mutation of the prothrombin gene and C677T polymorphism of the methylenetetrahydrofolate reductase (MTHFR) gene) with preeclampsia was investigated in a north-eastern Italian population.

Methods

Fifty-eight preeclamptic (PE) women and 74 normal pregnancies were evaluated. Genotypes were determined by polymerase chain reaction.

Results

The frequency of heterozygous carriers of the factor V Leiden was similar between PE women (5.2%) compared to the control subjects (4.1%; p 0.76). Also the frequencies of G20210A and C677T mutations were similar between PE and control subjects.

Conclusions

In this population, we found no difference in the prevalence of genetic risk factors for thrombosis in women with preeclampsia compared with control subjects."xsd:string
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http://purl.uniprot.org/citations/11961379http://purl.uniprot.org/core/author"Fabbro D."xsd:string
http://purl.uniprot.org/citations/11961379http://purl.uniprot.org/core/author"Damante G."xsd:string
http://purl.uniprot.org/citations/11961379http://purl.uniprot.org/core/author"D'Elia A.V."xsd:string
http://purl.uniprot.org/citations/11961379http://purl.uniprot.org/core/author"Petraglia F."xsd:string
http://purl.uniprot.org/citations/11961379http://purl.uniprot.org/core/author"Colaone R."xsd:string
http://purl.uniprot.org/citations/11961379http://purl.uniprot.org/core/author"Di Leonardo C."xsd:string
http://purl.uniprot.org/citations/11961379http://purl.uniprot.org/core/author"Driul L."xsd:string
http://purl.uniprot.org/citations/11961379http://purl.uniprot.org/core/author"Florio P."xsd:string
http://purl.uniprot.org/citations/11961379http://purl.uniprot.org/core/author"Giacomello R."xsd:string
http://purl.uniprot.org/citations/11961379http://purl.uniprot.org/core/author"Marchesoni D."xsd:string
http://purl.uniprot.org/citations/11961379http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/11961379http://purl.uniprot.org/core/name"Gynecol Obstet Invest"xsd:string
http://purl.uniprot.org/citations/11961379http://purl.uniprot.org/core/pages"84-87"xsd:string
http://purl.uniprot.org/citations/11961379http://purl.uniprot.org/core/title"Frequency of factor V, prothrombin and methylenetetrahydrofolate reductase gene variants in preeclampsia."xsd:string
http://purl.uniprot.org/citations/11961379http://purl.uniprot.org/core/volume"53"xsd:string
http://purl.uniprot.org/citations/11961379http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11961379
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