| http://purl.uniprot.org/citations/11970983 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11970983 | http://www.w3.org/2000/01/rdf-schema#comment | "NF-kappa B is a ubiquitously expressed transcription factor involved in the regulation of innate and adaptive immunity. As part of studies to define the role of various NF-kappa B family members in Th cell development and maintenance, we infected NF-kappa B2(-/-) and control mice with Leishmania major and followed disease progression. NF-kappa B2(-/-) mice on a normally resistant background develop chronic nonhealing lesions associated with uncontrolled parasite replication and a failure to develop an IFN-gamma response. We show that there are no intrinsic defects in Th cell differentiation in the absence of NF-kappa B2. Indeed, NF-kappa B2(-/-) T cells are able to develop a Th1 phenotype and protect recombination-activating gene(-/-) mice from progressive cutaneous leishmaniasis. We demonstrate instead that the susceptibility of NF-kappa B2(-/-) mice to L. major is the result of an IL-12 deficiency, and we provide evidence for a specific impairment in CD40-induced IL-12 production by macrophages lacking this transcription factor."xsd:string |
| http://purl.uniprot.org/citations/11970983 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.168.9.4406"xsd:string |
| http://purl.uniprot.org/citations/11970983 | http://purl.uniprot.org/core/author | "Scott P."xsd:string |
| http://purl.uniprot.org/citations/11970983 | http://purl.uniprot.org/core/author | "Hunter C.A."xsd:string |
| http://purl.uniprot.org/citations/11970983 | http://purl.uniprot.org/core/author | "Caamano J."xsd:string |
| http://purl.uniprot.org/citations/11970983 | http://purl.uniprot.org/core/author | "Speirs K."xsd:string |
| http://purl.uniprot.org/citations/11970983 | http://purl.uniprot.org/core/author | "Goldschmidt M.H."xsd:string |
| http://purl.uniprot.org/citations/11970983 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11970983 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/11970983 | http://purl.uniprot.org/core/pages | "4406-4413"xsd:string |
| http://purl.uniprot.org/citations/11970983 | http://purl.uniprot.org/core/title | "NF-kappa B2 is required for optimal CD40-induced IL-12 production but dispensable for Th1 cell Differentiation."xsd:string |
| http://purl.uniprot.org/citations/11970983 | http://purl.uniprot.org/core/volume | "168"xsd:string |
| http://purl.uniprot.org/citations/11970983 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11970983 |
| http://purl.uniprot.org/citations/11970983 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11970983 |
| http://purl.uniprot.org/uniprot/#_A0A494B9Y5-mappedCitation-11970983 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11970983 |
| http://purl.uniprot.org/uniprot/#_A0A494BAQ2-mappedCitation-11970983 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11970983 |
| http://purl.uniprot.org/uniprot/#_Q3UV15-mappedCitation-11970983 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11970983 |
| http://purl.uniprot.org/uniprot/#_Q4U105-mappedCitation-11970983 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11970983 |
| http://purl.uniprot.org/uniprot/#_Q4U106-mappedCitation-11970983 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11970983 |
| http://purl.uniprot.org/uniprot/#_Q4U108-mappedCitation-11970983 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11970983 |
| http://purl.uniprot.org/uniprot/#_Q3UG25-mappedCitation-11970983 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11970983 |
| http://purl.uniprot.org/uniprot/#_Q3U5V4-mappedCitation-11970983 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11970983 |
| http://purl.uniprot.org/uniprot/#_Q3ULT8-mappedCitation-11970983 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11970983 |
| http://purl.uniprot.org/uniprot/#_Q9WTK5-mappedCitation-11970983 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11970983 |