| http://purl.uniprot.org/citations/11973299 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11973299 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11973299 | http://www.w3.org/2000/01/rdf-schema#comment | "Spore formation in Saccharomyces cerevisiae requires the de novo synthesis of prospore membranes and spore walls. Ady3p has been identified as an interaction partner for Mpc70p/Spo21p, a meiosis-specific component of the outer plaque of the spindle pole body (SPB) that is required for prospore membrane formation, and for Don1p, which forms a ring-like structure at the leading edge of the prospore membrane during meiosis II. ADY3 expression has been shown to be induced in midsporulation. We report here that Ady3p interacts with additional components of the outer and central plaques of the SPB in the two-hybrid assay. Cells that lack ADY3 display a decrease in sporulation efficiency, and most ady3Delta/ady3Delta asci that do form contain fewer than four spores. The sporulation defect in ady3Delta/ady3Delta cells is due to a failure to synthesize spore wall polymers. Ady3p forms ring-like structures around meiosis II spindles that colocalize with those formed by Don1p, and Don1p rings are absent during meiosis II in ady3Delta/ady3Delta cells. In mpc70Delta/mpc70Delta cells, Ady3p remains associated with SPBs during meiosis II. Our results suggest that Ady3p mediates assembly of the Don1p-containing structure at the leading edge of the prospore membrane via interaction with components of the SPB and that this structure is involved in spore wall formation."xsd:string |
| http://purl.uniprot.org/citations/11973299 | http://purl.org/dc/terms/identifier | "doi:10.1093/genetics/160.4.1439"xsd:string |
| http://purl.uniprot.org/citations/11973299 | http://purl.org/dc/terms/identifier | "doi:10.1093/genetics/160.4.1439"xsd:string |
| http://purl.uniprot.org/citations/11973299 | http://purl.uniprot.org/core/author | "Neiman A.M."xsd:string |
| http://purl.uniprot.org/citations/11973299 | http://purl.uniprot.org/core/author | "Neiman A.M."xsd:string |
| http://purl.uniprot.org/citations/11973299 | http://purl.uniprot.org/core/author | "Nickas M.E."xsd:string |
| http://purl.uniprot.org/citations/11973299 | http://purl.uniprot.org/core/author | "Nickas M.E."xsd:string |
| http://purl.uniprot.org/citations/11973299 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11973299 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11973299 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
| http://purl.uniprot.org/citations/11973299 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
| http://purl.uniprot.org/citations/11973299 | http://purl.uniprot.org/core/pages | "1439-1450"xsd:string |
| http://purl.uniprot.org/citations/11973299 | http://purl.uniprot.org/core/pages | "1439-1450"xsd:string |
| http://purl.uniprot.org/citations/11973299 | http://purl.uniprot.org/core/title | "Ady3p links spindle pole body function to spore wall synthesis in Saccharomyces cerevisiae."xsd:string |
| http://purl.uniprot.org/citations/11973299 | http://purl.uniprot.org/core/title | "Ady3p links spindle pole body function to spore wall synthesis in Saccharomyces cerevisiae."xsd:string |
| http://purl.uniprot.org/citations/11973299 | http://purl.uniprot.org/core/volume | "160"xsd:string |
| http://purl.uniprot.org/citations/11973299 | http://purl.uniprot.org/core/volume | "160"xsd:string |
| http://purl.uniprot.org/citations/11973299 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11973299 |
| http://purl.uniprot.org/citations/11973299 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11973299 |
| http://purl.uniprot.org/citations/11973299 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11973299 |
| http://purl.uniprot.org/citations/11973299 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11973299 |
| http://purl.uniprot.org/uniprot/Q07732 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/11973299 |
| http://purl.uniprot.org/uniprot/Q12411 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/11973299 |