| http://purl.uniprot.org/citations/11980907 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11980907 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11980907 | http://www.w3.org/2000/01/rdf-schema#comment | "Apoptosis-inducing factor (AIF) is a mitochondrial flavoprotein that triggers caspase-independent apoptosis. We describe here the cloning and characterization of a novel AIF-homologous molecule designated AMID (AIF-homologous mitochondrion-associated inducer of death). AMID lacks a mitochondrial localization sequence but shares significant homology with AIF and NADH oxidoreductases from bacteria to mammalian species. Immunofluorescent staining and biochemical experiments indicated that AMID was co-localized with mitochondria. Overexpression of AMID induced cell death with characteristic apoptotic morphology. Furthermore, AMID-induced apoptosis was independent of caspase activation and p53 and was not inhibited by Bcl-2. These findings suggest that AMID induces a novel caspase-independent apoptotic pathway."xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m202285200"xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m202285200"xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/author | "Wu M."xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/author | "Wu M."xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/author | "Zhai Z."xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/author | "Zhai Z."xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/author | "Xu L.-G."xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/author | "Xu L.-G."xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/author | "Shu H.-B."xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/author | "Shu H.-B."xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/pages | "25617-25623"xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/pages | "25617-25623"xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/title | "AMID, an apoptosis-inducing factor-homologous mitochondrion-associated protein, induces caspase-independent apoptosis."xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/title | "AMID, an apoptosis-inducing factor-homologous mitochondrion-associated protein, induces caspase-independent apoptosis."xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/volume | "277"xsd:string |
| http://purl.uniprot.org/citations/11980907 | http://purl.uniprot.org/core/volume | "277"xsd:string |