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http://purl.uniprot.org/citations/11981870http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11981870http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11981870http://www.w3.org/2000/01/rdf-schema#comment"In 1993, we reported the presence of an IgM-associated peptide (M(r) 44 kDa; pI 5.45) in all immunoglobulin M (IgM) fractions purified from plasma/serum by various methods. This peptide was absent in Ig fractions of non-IgM isotypes. The N-terminal sequence was determined as being APPSGVRLVGGLH. To gain insight into the nature of this peptide, we further analyzed, using modern proteomic tools, the IgM-associated peptide isolated from cryoglobulins. Mass spectrometry revealed three peptides of different masses: 2203.13 (ELGCGAASGTPSGILYEPPAEK), 1564.83 (KPIWLSQMSCSGR), and 1544.77 (EATLQDCPSGPWGK). Theses sequences together with the already known N-terminal sequence allowed us to identity the IgM-associated peptide as Sp alpha (O43866 in TrEMBL database; CD5 antigen-like). Sp alpha is a member of the scavenger receptor cysteine-rich superfamily of proteins. This family includes the T-and B-cell antigens CD5 and CD6, and several of its members influence immune cell fate. Our finding may have important implications in the understanding of the homeostasis of IgM antibodies."xsd:string
http://purl.uniprot.org/citations/11981870http://purl.org/dc/terms/identifier"doi:10.1002/1522-2683(200204)23:7/8<1203::aid-elps1203>3.0.co;2-1"xsd:string
http://purl.uniprot.org/citations/11981870http://purl.org/dc/terms/identifier"doi:10.1002/1522-2683(200204)23:7/8<1203::aid-elps1203>3.0.co;2-1"xsd:string
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/author"Hochstrasser D.F."xsd:string
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/author"Hochstrasser D.F."xsd:string
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/author"Sanchez J.-C."xsd:string
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/author"Sanchez J.-C."xsd:string
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/author"Scherl A."xsd:string
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/author"Scherl A."xsd:string
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/author"Schneider P."xsd:string
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/author"Schneider P."xsd:string
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/author"Schifferli J.A."xsd:string
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/author"Schifferli J.A."xsd:string
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/author"Duchosal M.A."xsd:string
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/author"Duchosal M.A."xsd:string
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/author"Tissot J.D."xsd:string
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/author"Tissot J.D."xsd:string
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/author"Vuadens F."xsd:string
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/author"Vuadens F."xsd:string
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/name"Electrophoresis"xsd:string
http://purl.uniprot.org/citations/11981870http://purl.uniprot.org/core/name"Electrophoresis"xsd:string