| http://purl.uniprot.org/citations/11997190 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11997190 | http://www.w3.org/2000/01/rdf-schema#comment | "We studied the influence of thyroid hormones and vitamin A status on the regulation of UDP-glucuronosyltransferase (UGT) expression and the glucuronidation of thyroid hormones by UGTs. For this, we used an original model of rats fed with different vitamin A diets and implanted subcutaneously by osmotic minipumps delivering vehicle or thyroid hormones, which permitted the control of plasma thyroid hormone concentrations. The activity and expression of family 1 UGTs are correlated and were significantly modified by both thyroid status and amounts of retinol in the diet. Dietary vitamin A did not perturbe the UGT1A expression in thyroidectomized animals. Thyroid hormones and dietary vitamin A did not affect the activity and expression of family 2 UGTs. We conclude that thyroid hormones and vitamin A are co-regulator of the UGT1 family expression, without affecting the UGT2 family; by modifying activity and expression of the bilirubin UOT isoform, a member of UGT1 family, thyroid hormone reduced the glucuronidation of T4 and rT3."xsd:string |
| http://purl.uniprot.org/citations/11997190 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0303-7207(01)00681-5"xsd:string |
| http://purl.uniprot.org/citations/11997190 | http://purl.uniprot.org/core/author | "Artur Y."xsd:string |
| http://purl.uniprot.org/citations/11997190 | http://purl.uniprot.org/core/author | "Goudonnet H."xsd:string |
| http://purl.uniprot.org/citations/11997190 | http://purl.uniprot.org/core/author | "Heydel J.M."xsd:string |
| http://purl.uniprot.org/citations/11997190 | http://purl.uniprot.org/core/author | "Haberkorn V."xsd:string |
| http://purl.uniprot.org/citations/11997190 | http://purl.uniprot.org/core/author | "Mounie J."xsd:string |
| http://purl.uniprot.org/citations/11997190 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/11997190 | http://purl.uniprot.org/core/name | "Mol Cell Endocrinol"xsd:string |
| http://purl.uniprot.org/citations/11997190 | http://purl.uniprot.org/core/pages | "167-175"xsd:string |
| http://purl.uniprot.org/citations/11997190 | http://purl.uniprot.org/core/title | "Vitamin A modulates the effects of thyroid hormone on UDP-glucuronosyltransferase expression and activity in rat liver."xsd:string |
| http://purl.uniprot.org/citations/11997190 | http://purl.uniprot.org/core/volume | "190"xsd:string |
| http://purl.uniprot.org/citations/11997190 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11997190 |
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